A lipid-soluble internal ester of PGF2α
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Prostaglandin F2α 1,9-lactone

Item No. 16130

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
9α,11α,15S-trihydroxy-prosta-5Z,13E-dien-1-oic acid, θ-lactone
CAS Number
55314-48-2
Synonyms
  • PGF2α 1,9-lactone
Molecular Formula
C20H32O4
Formula Weight
336.5
Purity
≥99%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: >20 mg/mlDMSO: >10 mg/mlEthanol: >100 mg/mlEthanol:PBS (30:70): 8 mg/mlPBS pH 7.2: <50 µg/ml
SMILES
O[C@H]1[C@H](/C=C/[C@@H](O)CCCCC)[C@@H](C/C=C\CCC2)[C@@H](OC2=O)C1
InChi Code
InChI=1S/C20H32O4/c1-2-3-6-9-15(21)12-13-16-17-10-7-4-5-8-11-20(23)24-19(17)14-18(16)22/h4,7,12-13,15-19,21-22H,2-3,5-6,8-11,14H2,1H3/b7-4-,13-12+/t15-,16+,17+,18+,19-/m0/s1
InChi Key
ZVWMOTMHZYWJPF-WTKFZEAQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    5 mg

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    10 mg

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    Product Description

    Prostaglandin F2α (PGF2α) 1,9-lactone is a lipid-soluble internal ester of PGF2α. It is resistant to hydrolysis by human plasma esterases even after incubation for 20 hours under physiological conditions.1 PGF2α 1,9-lactone exhibits little antifertility and vasoactivity compared to PGF2α.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bundy, G.L., Peterson, D.C., Cornette, J.C., et al. Synthesis and biological activity of prostaglandin lactones. J. Med. Chem. 26(8), 1089-1099 (1983).