A pyrimidine nucleoside
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5-Methyl-2'-deoxycytidine

Item No. 16166

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2'-deoxy-5-methyl-cytidine
CAS Number
838-07-3
Synonyms
  • 5-Methyldeoxycytidine
Molecular Formula
C10H15N3O4
Formula Weight
241.2
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 5 mg/mlDMSO: 20 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
280 nm
SMILES
O=C(N=C(N)C(C)=C1)N1[C@H]2C[C@H](O)[C@@H](CO)O2
InChi Code
InChI=1S/C10H15N3O4/c1-5-3-13(10(16)12-9(5)11)8-2-6(15)7(4-14)17-8/h3,6-8,14-15H,2,4H2,1H3,(H2,11,12,16)/t6-,7+,8+/m0/s1
InChi Key
LUCHPKXVUGJYGU-XLPZGREQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 mg

    $49

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    1 g

    $93

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    5 g

    $376

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    Product Description

    5-Methyl-2'-deoxycytidine is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo DNA methylation.1 It has been used in epigenetics research to investigate the dynamics of DNA methylation pattern in the control of gene expression.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Christman, J.K., Sheikhnejad, G., Marasco, C.J., et al. 5-Methyl-2'-deoxycytidine in single-stranded DNA can act in cis to signal de novo DNA methylation. Proc. Natl. Acad. Sci. USA 92(16), 7347-7351 (1995).

    2. Testillano, P.S., Solís, M.T., and Risueño, M.C. The 5-methyl-deoxy-cytidine (5mdC) localization to reveal in situ the dynamics of DNA methylation chromatin pattern in a variety of plant organ and tissue cells during development. Physiol. Plant. 149(1), 104-113 (2013).