A metabolite of dimetridazole
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Hydroxy Dimetridazole

Item No. 16208

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-methyl-5-nitro-1H-imidazole-2-methanol
CAS Number
936-05-0
Synonyms
  • HMMNI
  • 2-Hydroxymethyl-1-methyl-5-Nitroimidazole
Molecular Formula
C5H7N3O3
Formula Weight
157.1
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 3 mg/mlPBS (pH 7.2): 1 mg/ml
λmax
304 nm
SMILES
CN1C(CO)=NC=C1[N+]([O-])=O
InChi Code
InChI=1S/C5H7N3O3/c1-7-4(3-9)6-2-5(7)8(10)11/h2,9H,3H2,1H3
InChi Key
JSAQDPJIVQMBAY-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

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    50 mg

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    100 mg

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    Cayman Chemical
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    Product Description

    Dimetridazole is a nitroimidazole-based compound with antibacterial and anticoccidial activity.1 It was once widely used in the treatment of parasitic infections in poultry, cattle, swine and farmed fish until suspected to be carcinogenic and mutagenic to humans.2 Hydroxy dimetridazole is a metabolite of dimetridazole that may be useful for identifying this nitroimidazole in various agricultural samples through liquid chromatography–tandem mass spectrometry and other methods.2,3,4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Jokipii, L., and Jokipii, A.M. Comparative evaluation of the 2-methyl-5-nitroimidazole compounds dimetridazole, metronidazole, secnidazole, ornidazole, tinidazole, carnidazole, and panidazole against Bacteroides fragilis and other bacteria of the Bacteroides fragilis group. Antimicrob. Agents Chemother. 28(4), 561-564 (1985).

    2. Sakamoto, M., Takeba, K., Sasamoto, T., et al. Determination of dimetridazole, metronidazole and ronidazole in salmon and honey by liquid chromatography coupled with tandem mass spectrometry. Shokuhin Eiseigaku Zasshi 52(1), 51-58 (2011).

    3. Tölgyesi, A., Sharma, V.K., Fekete, S., et al. Development of a rapid method for the determination and confirmation of nitroimidazoles in six matrices by fast liquid chromatography-tandem mass spectrometry. J. Pharm. Biomed. Anal. 64-65, 40-48 (2012).

    4. Mohamed, R., Mottier, P., Treguier, L., et al. Use of molecularly imprinted solid-phase extraction sorbent for the determination of four 5-nitroimidazoles and three of their metabolites from egg-based samples before tandem LC-ESIMS/MS analysis. J. Agric. Food Chem. 56(10), 3500-3508 (2008).