A deoxynucleotide
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Product Type

Biochemicals
Nucleotides/Nucleosides

Research Area

2'-Deoxyadenosine-5'-monophosphate (hydrate)

Item No. 16218

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2'-deoxy-5'-adenylic acid, hydrate
CAS Number
653-63-4
Molecular Formula
C10H14N5O6P • XH2O
Formula Weight
331.2
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 1 mg/ml
λmax
210, 260 nm
SMILES
NC1=NC=NC2=C1N=CN2[C@H]3C[C@H](O)[C@@H](COP(O)(O)=O)O3.O
InChi Code
InChI=1S/C10H14N5O6P.H2O/c11-9-8-10(13-3-12-9)15(4-14-8)7-1-5(16)6(21-7)2-20-22(17,18)19;/h3-7,16H,1-2H2,(H2,11,12,13)(H2,17,18,19);1H2/t5-,6+,7+;/m0./s1
InChi Key
QQMAPZSBBNPXKS-VWZUFWLJSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    500 mg

    $49

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    1 g

    $86

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    5 g

    $306

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    Product Description

    2’-Deoxyadenosine-5'-monophosphate is a derivative of the nucleic acid, AMP, in which the hydroxyl group on the 2' carbon of the pentose has been reduced to a hydrogen atom. It has been used in the synthesis of novel photoaffinity labels for incorporation into DNA and to study adenosine-based interactions during DNA synthesis and DNA damage.1,2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Zofall, M., and Bartholomew, B. Two novel dATP analogs for DNA photoaffinity labeling. Nucleic Acids Res. 28(21), 4382-4390 (2000).

    2. Li, Y.M., Han, Z.H., Jiang, S.H., et al. Fast repairing of oxidized OH radical adducts of dAMP and dGMP by phenylpropanoid glycosides from Scrophularia ningpoensis Hemsl. Acta Pharmacol. Sin. 21(12), 1125-1128 (2000).

    3. Duarte, V., Muller, J.G., and Burrows, C.J. Insertion of dGMP and dAMP during in vitro DNA synthesis opposite an oxidized form of 7,8-dihydro-8-oxoguanine. Nucleic Acids Res. 27(2), 496-502 (1999).