The major metabolite of α-phenyl-α-(2-pyridyl)thioacetamide
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α-Phenyl-α-(2-pyridyl)acetonitrile

Item No. 16224

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
α-phenyl-2-pyridineacetonitrile
CAS Number
5005-36-7
Synonyms
  • NSC 16276
  • 2-Pyridylphenylacetonitrile
Molecular Formula
C13H10N2
Formula Weight
194.2
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMF:PBS(pH 7.2)(1:1): 0.5 mg/mlDMSO: 25 mg/mlEthanol: 10 mg/ml
λmax
260 nm
SMILES
N#CC(C1=CC=CC=C1)C2=CC=CC=N2
InChi Code
InChI=1S/C13H10N2/c14-10-12(11-6-2-1-3-7-11)13-8-4-5-9-15-13/h1-9,12H
InChi Key
CAXNYFPECZCGFK-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 g

    $72

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    Product Description

    α-Phenyl-α-(2-pyridyl)thioacetamide, also known as antigastrin and SC-15396, is an inhibitor of gastric acid secretion.1 α-Phenyl-α-(2-pyridyl)acetonitrile is the major metabolite of α-phenyl-α-(2-pyridyl)thioacetamide produced by the supernatant fraction of rat liver homogenate.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Håkanson, R., and Liedberg, G. Activation of rat stomach histidine decarboxylase after inhibition of acid secretion with 2-phenyl-2-(2-pyridyl)-thioacetamide (SC-15396). Experientia 27(9), 1045-1046 (1971).

    2. Gibson, M.J., and Hunter, W.H. The metabolism of thioamides by the supernatant fraction of rat liver homogenate. J. Pharm. Pharmacol. 21(Suppl 1), 195S-198S (1969).