A positive allosteric modulator of mGluR4
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

VU0364439

Item No. 16296

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-[3-chloro-4-[[(2-chlorophenyl)amino]sulfonyl]phenyl]-2-pyridinecarboxamide
CAS Number
1246086-78-1
Molecular Formula
C18H13Cl2N3O3S
Formula Weight
422.3
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 3 mg/mlDMSO: 3 mg/mlDMSO:PBS (pH 7.2) (1:5): 0.16 mg/ml
λmax
280 nm
SMILES
O=C(C1=NC=CC=C1)NC2=CC=C(S(NC3=CC=CC=C3Cl)(=O)=O)C(Cl)=C2
InChi Code
InChI=1S/C18H13Cl2N3O3S/c19-13-5-1-2-6-15(13)23-27(25,26)17-9-8-12(11-14(17)20)22-18(24)16-7-3-4-10-21-16/h1-11,23H,(H,22,24)
InChi Key
IXHCGJXBIHHIEF-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $36

    Add

    5 mg

    $120

    Add

    10 mg

    $186

    Add

    50 mg

    $587

    Add
    Product Description

    VU0364439 is a positive allosteric modulator of metabotropic glutamate receptor 4 (mGluR4) that potentiates glutamate responses in CHO cells expressing recombinant human mGluR4 (EC50 = 19.8 nM).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Engers, D.W., Gentry, P.R., Williams, R., et al. Synthesis and SAR of novel, 4-(phenylsulfamoyl)phenylacetamide mGlu4 positive allosteric modulators (PAMs) identified by functional high-throughput screening (HTS). Bioorg. Med. Chem. Lett. 20(17), 5175-5178 (2010).