An inhibitor of retinoid-induced AP-1 signaling
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SR 11302

Item No. 16338

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(2E,4E,6Z,8E)-3-methyl-7-(4-methylphenyl)-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid
CAS Number
160162-42-5
Molecular Formula
C26H32O2
Formula Weight
376.5
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMF:PBS(pH7.2) (1:2): 0.33 mg/mlDMSO: 10 mg/mlEthanol: 0.5 mg/ml
λmax
360 nm
SMILES
CC1=C(/C=C/C(C2=CC=C(C)C=C2)=C/C=C/C(C)=C/C(O)=O)C(C)(C)CCC1
InChi Code
InChI=1S/C26H32O2/c1-19-11-13-23(14-12-19)22(10-6-8-20(2)18-25(27)28)15-16-24-21(3)9-7-17-26(24,4)5/h6,8,10-16,18H,7,9,17H2,1-5H3,(H,27,28)/b8-6+,16-15+,20-18+,22-10-
InChi Key
RQANARBNMTXCDM-DKOHIBGUSA-N
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $49

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    5 mg

    $178

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    10 mg

    $259

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    25 mg

    $527

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    Product Description

    SR 11302 is a synthetic retinoid that inhibits AP-1 activity without activating transcription through RARE.1 It significantly suppresses both AP-1 activation and phorbol ester-induced papilloma formation in mice when applied topically (0.1 µM).2 SR 11302 is used to elucidate the role of AP-1 in various signaling pathways.3,4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

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