A water-soluble PGF2β derivative
Related Products
Alternative(s)
16410Prostaglandin F2β
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Prostaglandin F2β (tromethamine salt)

Item No. 16420

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
9β,11α,15S-trihydroxy-prosta-5Z,13E-dien-1-oic acid, tris(hydroxymethyl)aminomethane salt
CAS Number
89847-02-9
Synonyms
  • 9β-PGF2α (tromethamine salt)
  • PGF2β (tromethamine salt)
Molecular Formula
C20H33O5 • C4H12NO3
Formula Weight
475.6
Purity
≥99%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
Acetone: >5 mg/ml (from PGF2a THAM)Acetonitrile: >5 mg/ml (from PGF2a THAM)DMSO: >50 mg/ml (from PGF2a THAM)Ethanol: >50 mg/ml (from PGF2a THAM)Methanol: >100 mg/ml (from PGF2a THAM)PBS pH 7.2: >25 mg/ml (from PGF2a THAM)
SMILES
O[C@H]1[C@H](C/C=C\CCCC([O-])=O)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1.[NH3+]C(CO)(CO)CO
InChi Code
InChI=1S/C20H34O5.C4H11NO3/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25;5-4(1-6,2-7)3-8/h4,7,12-13,15-19,21-23H,2-3,5-6,8-11,14H2,1H3,(H,24,25);6-8H,1-3,5H2/b7-4-,13-12+;/t15-,16+,17+,18+,19+;/m0./s1
InChi Key
IYGXEHDCSOYNKY-ILQMKDCTSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    1 mg

    $93

    Add

    5 mg

    $406

    Add

    10 mg

    $717

    Add
    Lipid Resource Center
    Discover Products & Resources for Lipid Research
    • High-purity lipid standards
    • Lipid roles in biology
    • Lipids in health & disease
    • Lipids for pharmaceutical development
    • Protocols, advice, & resources
    EXPLORE NOW
    Product Description

    Prostaglandin F2β (PGF2β) (tromethamine salt) is a derivative of PGF2β (Item No. 16410) with increased water solubility. PGF2β is the 9β-hydroxy stereoisomer of PGF2α (Item No. 16010). It is much less active than PGF2α in antifertility and bronchoconstrictor activities.1,2,3 PGF2β exhibits bronchodilating activity in guinea pigs and cats and antagonizes the bronchoconstrictor activity of PGF2α.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Miller, W.L., and Sutton, M.J. Relative biological activity of certain prostaglandins and their enantiomers. Prostaglandins 11(1), 77-84 (1976).

    2. Gardiner, P.J., and Collier, H.O.J. Specific receptors for prostaglandins in airways. Prostaglandins 19(6), 819-841 (1980).

    3. Rosenthale, M.E., Dervinis, A., Kassarich, J., et al. Bronchodilating properties of the prostaglandin F2β in the guinea pig and cat. Prostaglandins 3(6), 767-772 (1973).