A bis-phosphorylated derivative of α-D-glucose
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α-D-Glucose-1,6-bisphosphate (cyclohexyl ammonium salt hydrate)

Item No. 16464

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
α-D-glucopyranose, 1,6-bis(dihydrogen phosphate), cyclohexanamine (1:4), hydrate
Synonyms
  • D-Glucose-1,6-diphosphate
  • Glc-1,6-P2
Molecular Formula
C6H14O12P2 • 4C6H13N [XH2O]
Formula Weight
736.8
Purity
≥95%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 10 mg/ml
SMILES
O[C@@H]1[C@@H](O)[C@H](O)[C@@H](COP(O)(O)=O)O[C@@H]1OP(O)(O)=O.NC2CCCCC2.NC3CCCCC3.NC4CCCCC4.NC5CCCCC5.O
InChi Code
InChI=1S/7C6H13N.C6H14O12P2.H2O/c7*7-6-4-2-1-3-5-6;7-3-2(1-16-19(10,11)12)17-6(5(9)4(3)8)18-20(13,14)15;/h7*6H,1-5,7H2;2-9H,1H2,(H2,10,11,12)(H2,13,14,15);1H2/t;;;;;;;2-,3-,4+,5-,6-;/m.......1./s1
InChi Key
UXTCMIJEZNTXPS-VCQKQOJISA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $49

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    5 mg

    $178

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    10 mg

    $329

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    25 mg

    $587

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    Product Description

    α-D-Glucose-1,6-bisphosphate is a bis-phosphorylated derivative of α-D-glucose that has roles in carbohydrate metabolism.1 It is the product of the reaction of glucose-1- or 6-phosphate with glucose-1,6-bisphosphate synthase (PGM2LI) in the conversion of 1,3-bisphosphoglycerate to 3-phosphoglycerate.2 It is also a cofactor for the bacterial enzyme phosphopentomutase.3,4 α-D-Glucose-1,6-bisphosphate has been used in the study of carbohydrate metabolism.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Beitner, R. Regulation of carbohydrate metabolism by glucose 1,6-bisphosphate in extrahepatic tissues; comparison with fructose 2,6-bisphosphate. Int. J. Biochem. 22(6), 553-557 (1990).

    2. Maliekal, P., Sokolova, T., Vertommen, D., et al. Molecular identification of mammalian phosphopentomutase and glucose-1,6-bisphosphate synthase, two members of the α-D-phosphohexomutase family. The Journal of Biological Chemisty 282(44), 31844-31851 (2007).

    3. Moustafa, H.M.A., Zaghloul, T.I., and Zhang, Y.-H.P. A simple assay for determining activities of phosphopentomutase from a hyperthermophilic bacterium Thermotoga maritima. Anal. Biochem. 501, 75-81 (2016).

    4. Panosian, T.D., Nannemann, D.P., Watkins, G.R., et al. Bacillus cereus phosphopentomutase is an alkaline phosphatase family member that exhibits an altered entry point into the catalytic cycle. The Journal of Biological Chemisty 286(10), 8043-8054 (2011).