A β-adrenergic agonist
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Labeled Version(s)
22903Zilpaterol-d7
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Zilpaterol (hydrochloride)

Item No. 16484

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(6R,7R)-rel-4,5,6,7-tetrahydro-7-hydroxy-6-[(1-methylethyl)amino]-imidazo[4,5,1-jk][1]benzazepin-2(1H)-one, monohydrochloride
CAS Number
119520-06-8
Synonyms
  • RU-42173
Molecular Formula
C14H19N3O2 • HCl
Formula Weight
297.8
Purity
≥95%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 0.1 mg/mlDMSO: 1 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
210, 234, 287 nm
SMILES
O=C1NC2=CC=CC3=C2N1CC[C@H](NC(C)C)[C@H]3O.Cl
InChi Code
InChI=1S/C14H19N3O2.ClH/c1-8(2)15-11-6-7-17-12-9(13(11)18)4-3-5-10(12)16-14(17)19;/h3-5,8,11,13,15,18H,6-7H2,1-2H3,(H,16,19);1H/t11-,13-;/m0./s1
InChi Key
GIEFXLLRTJNFGT-JZKFLRDJSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Product Description

    Zilpaterol is a β-adrenergic receptor agonist that putatively through activation of protein kinase A increases protein synthesis in skeletal muscle fibers, as well as reduces lipogenesis and increases lipolysis in adipose tissues.1,2 It was approved by the FDA in 2006 as a veterinary food additive for the purpose of increasing lean body weight and improving feed efficiency in commercial beef cattle.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Avendaño-Reyes, L., Torres-Rodríguez, V., Meraz-Murullo, F.J., et al. Effects of two β-adrenergic agonists on finishing performance, carcass characteristics, and meat quality of feedlot steers. J. Anim. Sci. 84(12), 3259-3265 (2006).

    2. Miller, E.K., Chung, K.Y., Hutcheson, J.P., et al. Zilpaterol hydrochloride alters abundance of β-adrenergic receptors in bovine muscle cells but has little effect on de novo fatty acid biosynthesis in bovine subcutaneous adipose tissue explants. J. Anim. Sci. 90(4), 1317-1327 (2012).

    3. Delmore, R.J., Hodgen, J.M., and Johnson, B.J. Perspectives on the application of zilpaterol hydrochloride in the United States beef industry. J. Anim. Sci. 88(8), 2825-2828 (2010).