An acylated linker for click chemistry
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Product Categories

Product Type

Biochemicals
Lipids
Fatty Acids

Research Area

Lipid Biochemistry

Application

Click Chemistry

6-Azidohexanoic Acid

Item No. 16518

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
6-azido-hexanoic acid
CAS Number
79598-53-1
Synonyms
  • Click Tag™ 6-Azidohexanoic Acid
Molecular Formula
C6H11N3O2
Formula Weight
157.2
Purity
≥98%
Formulation (Request formulation change)
A neat oil
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
214 nm
SMILES
OC(CCCCCN=[N+]=[N-])=O
InChi Code
InChI=1S/C6H11N3O2/c7-9-8-5-3-1-2-4-6(10)11/h1-5H2,(H,10,11)
InChi Key
JCORXJUUSVCJEP-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    100 mg

    $36

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    250 mg

    $81

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    1 g

    $253

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    Product Description

    6-Azidohexanoic acid is a six carbon saturated fatty acid with an ω-terminal azide group. This terminal group allows conjugation with compounds containing alkyne groups through a copper(I)-catalyzed cycloaddition reaction, also known as click chemistry. 6-Azidohexanoic acid is commonly used as a linker that is first acylated to one compound to create a derivative that can then be joined to another compound using click chemistry.1,2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Alleti, R., Rao, V., Xu, L., et al. A solanesol-derived scaffold for multimerization of bioactive peptides. The Journal of Organic Chemistry 75(17), 5895-5903 (2010).

    2. Daumar, P., Wanger-Baumann, C.A., Pillarsetty, N., et al. Efficient 18F-labeling of large 37-amino-acid pHLIP peptide analogues and their biological evaluation. Bioconjug. Chem. 23(8), 1557-1566 (2012).

    3. Zolotarskaya, O.Y., Wagner, A.F., Beckta, J.M., et al. Synthesis of water-soluble camptothecin-polyoxetane conjugates via click chemistry. Mol. Pharm. 9(11), 3403-3408 (2012).