A mucoactive antioxidant
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Fudosteine

Item No. 16722

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
S-(3-hydroxypropyl)-L-cysteine
CAS Number
13189-98-5
Synonyms
  • SS320A
Molecular Formula
C6H13NO3S
Formula Weight
179.2
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 10 mg/ml
SMILES
OC([C@@H](N)CSCCCO)=O
InChi Code
InChI=1S/C6H13NO3S/c7-5(6(9)10)4-11-3-1-2-8/h5,8H,1-4,7H2,(H,9,10)/t5-/m0/s1
InChi Key
KINWYTAUPKOPCQ-YFKPBYRVSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    10 mg

    $36

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    25 mg

    $70

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    50 mg

    $120

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    100 mg

    $219

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    Product Description

    Fudosteine is a cysteine derivative that interferes with the increase in goblet cell number, expression of the mucin MUC5AC, and subsequent mucin secretion, in airways agonized with tobacco smoke, isoproterenol, lipopolysaccharide, TNF-α, or oxidants.1,2,3 Fudosteine, which is a thiol compound with antioxidant properties, limits NF-κB signaling and reduces inflammatory gene expression.3 It has greater bioavailability than N-acetyl-cysteine and increases cysteine levels in cells.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Takahashi, K., Mizuno, H., Ohno, H., et al. Effects of SS320A, a new cysteine derivative, on the change in the number of goblet cells induced by isoproterenol in rat tracheal epithelium. Jpn. J. Pharmacol. 77(1), 71-77 (1998).

    2. Rhee, C.K., Kang, C.M., You, M.B., et al. Effect of fudosteine on mucin production. Eur. Respir. J. 32(5), 1195-1202 (2008).

    3. Rahman, I. Pharmacological antioxidant strategies as therapeutic interventions for COPD. Biochim. Biophys. Acta 1822(5), 714-728 (2012).