An end product of phenylalanine metabolism in humans
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Product Categories

Product Type

Biochemicals
Amino Acids
Metabolites

Research Area

Endocrinology & Metabolism

Phenylacetyl L-Glutamine

Item No. 16724

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N2-(2-phenylacetyl)-L-glutamine
CAS Number
28047-15-6
Synonyms
  • NSC 203800
  • PAG
  • Phenylacetyl L-Gln
Molecular Formula
C13H16N2O4
Formula Weight
264.3
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 10 mg/mlPBS (pH 7.2): 2 mg/ml
SMILES
O=C(N[C@H](C(O)=O)CCC(N)=O)CC1=CC=CC=C1
InChi Code
InChI=1S/C13H16N2O4/c14-11(16)7-6-10(13(18)19)15-12(17)8-9-4-2-1-3-5-9/h1-5,10H,6-8H2,(H2,14,16)(H,15,17)(H,18,19)/t10-/m0/s1
InChi Key
JFLIEFSWGNOPJJ-JTQLQIEISA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    10 mg

    $54

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    25 mg

    $120

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    50 mg

    $209

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    100 mg

    $367

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    Product Description

    Phenylacetyl L-glutamine is an end product of phenylalanine metabolism in humans and primates.1 In a large number of other mammals, the corresponding end product is phenylacetylglycine.1 Phenylacetyl L-glutamine is excreted in urine, with urinary concentrations increasing with age.2,3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Moldave, K., and Meister, A. Synthesis of phenylacetylglutamine by human tissue. The Journal of Biological Chemisty 229(1), 463-476 (1957).

    2. Swann, J.R., Spagou, K., Lewis, M., et al. Microbial-mammalian cometabolites dominate the age-associated urinary metabolic phenotype in Taiwanese and American populations. J. Proteome Res. 12(7), 3166-3180 (2013).

    3. Collino, S., Montoliu, I., Martin, F.P.J., et al. Metabolic signatures of extreme longevity in northern Italian centenarians reveal a complex remodeling of lipids, amino acids, and gut microbiota metabolism. PLoS One 8(3), 1-12 (2013).