A stable PGF2α analog
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16,16-dimethyl Prostaglandin F2α

Item No. 16750

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
9α,11α,15R-trihydroxy-16,16-dimethyl-prosta-5Z,13E-dien-1-oic acid
CAS Number
39746-23-1
Synonyms
  • 16,16-dimethyl PGF2α
Molecular Formula
C22H38O5
Formula Weight
382.5
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
10 mM Na2CO3: >6.5 mg/mlDMF: >100 mg/mlDMSO: >100 mg/mlEthanol: >100 mg/mlPBS pH 7.2: >10 mg/ml
SMILES
O[C@H]1[C@H](/C=C/[C@@H](O)C(C)(C)CCCC)[C@@H](C/C=C\CCCC(O)=O)[C@@H](O)C1
InChi Code
InChI=1S/C22H38O5/c1-4-5-14-22(2,3)20(25)13-12-17-16(18(23)15-19(17)24)10-8-6-7-9-11-21(26)27/h6,8,12-13,16-20,23-25H,4-5,7,9-11,14-15H2,1-3H3,(H,26,27)/b8-6-,13-12+/t16-,17-,18+,19-,20-/m1/s1
InChi Key
YMRWVEHSLXJOCD-SCOYTADVSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $91

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    5 mg

    $399

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    10 mg

    $707

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    Product Description

    16,16-dimethyl PGF2α is a metabolically stable analog of PGF2α. It binds to the FP receptor on ovine luteal cells with slightly better affinity (159%) than PGF2α.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Balapure, A.K., Rexroad, C.E., Jr., Kawada, K., et al. Structural requirements for prostaglandin analog interaction with the ovine corpus luteum prostaglandin F2α receptor. Biochem. Pharmacol. 38(14), 2375-2381 (1989).