A stable PGF analog
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16-phenyl tetranor Prostaglandin F

Item No. 16770

Technical Information
Formal Name
(5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-4-phenyl-1-buten-1-yl]cyclopentyl]-5-heptenoic acid
CAS Number
38315-48-9
Synonyms
  • 16-phenyl tetranor PGF
Molecular Formula
C22H30O5
Formula Weight
Purity
≥99%
Formulation
A crystalline solid
DMF: >100 mg/mlDMSO: >100 mg/mlEthanol: >100 mg/mlPBS (pH 7.2): >0.8 mg/ml
SMILES
O[C@@H]1[C@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@@H](O)CC2=CC=CC=C2)[C@H](O)C1
InChi Code
InChI=1S/C22H30O5/c23-17(14-16-8-4-3-5-9-16)12-13-19-18(20(24)15-21(19)25)10-6-1-2-7-11-22(26)27/h1,3-6,8-9,12-13,17-21,23-25H,2,7,10-11,14-15H2,(H,26,27)/b6-1-,13-12+/t17-,18-,19-,20+,21-/m1/s1
InChi Key
AVUYLHQSIMTBCQ-SDMFVQJASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    16-phenyl tetranor Prostaglandin F (16-phenyl tetranor PGF) is a metabolically stable analog of PGF. The affinity of 16-phenyl tetranor PGF at the FP receptor of ovine luteal cells is poor (8.7%) compared to PGF.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Balapure, A.K., Rexroad, C.E., Jr., Kawada, K., et alStructural requirements for prostaglandin analog interaction with the ovine corpus luteum prostaglandin F receptor. Biochem. Pharmacol. 38(14), 2375-2381 (1989).