An isomer of fluprostenol
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15(S)-Fluprostenol

Item No. 16787

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic acid
CAS Number
54276-24-3
Molecular Formula
C23H29F3O6
Formula Weight
458.5
Purity
≥98%
Formulation (Request formulation change)
A 10 mg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 20 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 5 mg/ml
λmax
222, 277 nm
SMILES
O[C@@H]1[C@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/[C@H](O)COC2=CC(C(F)(F)F)=CC=C2)[C@H](O)C1
InChi Code
InChI=1S/C23H29F3O6/c24-23(25,26)15-6-5-7-17(12-15)32-14-16(27)10-11-19-18(20(28)13-21(19)29)8-3-1-2-4-9-22(30)31/h1,3,5-7,10-12,16,18-21,27-29H,2,4,8-9,13-14H2,(H,30,31)/b3-1-,11-10+/t16-,18+,19+,20-,21+/m0/s1
InChi Key
WWSWYXNVCBLWNZ-HBWANGNJSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

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    5 mg

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    10 mg

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    Product Description

    15(S)-Fluprostenol is an isomer of the FP receptor agonist fluprostenol (Item No. 16768).1 It is a potential active metabolite of 15(S)-fluprostenol isopropyl ester (Item No. 16788), which could act as an agonist at FP receptors albeit at a lower potency than the 15(R) epimer fluprostenol.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sorbera, L.A., and Castañer, J. Travoprost. Drugs Future 25(1), 41-45 (2000).