A keto derivative of an F-series prostaglandin and a metabolite of 17-phenyl trinor PGF2α ethyl amide
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15-keto-17-phenyl trinor Prostaglandin F2α

Item No. 16817

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E)-3-oxo-5-phenyl-1-penten-1-yl]cyclopentyl]-5-heptenoic acid
CAS Number
949564-89-0
Synonyms
  • 15-keto-17-phenyl trinor PGF2α
Molecular Formula
C23H30O5
Formula Weight
386.5
Purity
≥98%
Formulation (Request formulation change)
A 10 mg/ml solution in methyl acetate
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 25 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 2.5 mg/ml
SMILES
O[C@@H]1[C@H](C/C=C\CCCC(O)=O)[C@@H](/C=C/C(CCC2=CC=CC=C2)=O)[C@H](O)C1
InChi Code
InChI=1S/C23H30O5/c24-18(13-12-17-8-4-3-5-9-17)14-15-20-19(21(25)16-22(20)26)10-6-1-2-7-11-23(27)28/h1,3-6,8-9,14-15,19-22,25-26H,2,7,10-13,16H2,(H,27,28)/b6-1-,15-14+/t19-,20-,21+,22-/m1/s1
InChi Key
HHEYLKRDELKWGI-RKJYIPPQSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

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    Product Description

    15-keto-17-phenyl trinor Prostaglandin F2α (15-keto-17-phenyl trinor PGF2α) is a keto derivative of an F-series prostaglandin and a metabolite of the prostaglandin FP receptor agonist 17-phenyl trinor PGF2α ethyl amide (Item No. 16820).1,2 It is formed from 17-phenyl trinor PGF2α ethyl amide by 15-prostaglandin dehydrogenase (15-PGDH) and amidases via a 15-keto-17-phenyl trinor PGF2α ethyl amide (Item No. 10010405) intermediate.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Basu, S., and Stjernschantz, J. Δ13-reductase dependent metabolism of prostaglandins in the mammalian brain and eye. Prostaglandins Leukot. Essent. Fatty Acids 57(3), 305-310 (1997).

    2. Zezula, M., Ruszczak, M., Maruszak, W., et al. Development and validation of the stability indicating RP-UHPLC method for the determination of the chemical purity and assay of bimatoprost. J. Pharm. Biomed. Anal. 174, 348-359 (2019).