The major urinary metabolite of PGF2α
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tetranor-PGFM

Item No. 16840

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
9α,11α-dihydroxy-15-oxo-13,14-dihydro-2,3,4,5-tetranor-prostan-1,20-dioic acid
CAS Number
23109-94-6
Synonyms
  • tetranor-Prostaglandin F Metabolite
Molecular Formula
C16H26O7
Formula Weight
330.4
Purity
≥98%
Formulation (Request formulation change)
A 100 µg/ml solution in methyl acetate
Solubility(Learn about Variance in Solubility)
DMF: >100 mg/ml (from PGF2a)DMSO: >100 mg/ml (from PGF2a)Ethanol: >100 mg/ml (from PGF2a)PBS pH 7.2: >10 mg/ml (from PGF2a)
SMILES
O[C@H]1[C@H](CCC(CCCCC(O)=O)=O)[C@@H](CCC(O)=O)C(O)C1
InChi Code
InChI=1S/C16H26O7/c17-10(3-1-2-4-15(20)21)5-6-11-12(7-8-16(22)23)14(19)9-13(11)18/h11-14,18-19H,1-9H2,(H,20,21)(H,22,23)/t11-,12-,13-,14?/m1/s1
InChi Key
IGRHJCFWWOQYQE-ZHZAVPAVSA-N
Shipping & Storage Information
Storage
-80°C
Shipping
Dry ice in continental US; may vary elsewhere
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    25 µg

    $147

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    50 µg

    $277

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    100 µg

    $522

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    Product Description

    tetranor-PGFM is the major urinary metabolite of PGF2α.1,2,3,4 Normal healthy females excrete 7-13 µg of tetranor-PGFM per day compared to 11-59 µg/24 hours for healthy males.2 In pregnant females, tetranor-PGFM levels in the urine are 2 to 5-fold higher and diminish to pre-pregnancy levels soon after labor.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Granström, E., and Samuelsson, B. The structure of a urinary metabolite of prostaglandin F2α in man. J. Am. Chem. Soc. 91(12), 3398-3400 (1969).

    2. Granström, E., and Samuelsson, B. On the metabolism of prostaglandin F2α in female subjects. The Journal of Biological Chemisty 246(17), 5254-5263 (1971).

    3. Hamberg, M. Quantitative studies on prostaglandin synthesis in man III. Excretion of the major urinary metabolite of prostaglandins F1α and F2α during pregnancy. Life Sci. 14(2), 247-252 (1974).

    4. Hamberg, M. Quantitative studies on prostaglandin synthesis in man II. Determination of the major urinary metabolite of prostaglandins F1α and F2α. Anal. Biochem. 55(2), 368-378 (1973).

    Product Citations

    Sasaki, A., Fukuda, H., Shiida, N., et al. Determination of ω-6 and ω-3 PUFA metabolites in human urine samples using UPLC/MS/MS. Anal. Bioanal. Chem. 407(6), 1625-1639 (2015).