A turn-on fluorescent probe for H2S
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WSP-5

Item No. 16929

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl bis(2-(pyridin-2-yldisulfanyl)benzoate)
CAS Number
1593024-78-2
Synonyms
  • Washington State Probe-5
Molecular Formula
C44H26N2O7S4
Formula Weight
822.9
Purity
≥95%
Emission
525 nm
Excitation
502 nm
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 25 mg/ml
λmax
225 nm
SMILES
O=C(OC1=CC=C2C(OC3=C(C24C5=CC=CC=C5C(O4)=O)C=CC(OC(C6=CC=CC=C6SSC7=CC=CC=N7)=O)=C3)=C1)C8=C(SSC9=NC=CC=C9)C=CC=C8
InChi Code
InChI=1S/C44H26N2O7S4/c47-41(30-12-2-5-15-37(30)54-56-39-17-7-9-23-45-39)50-27-19-21-33-35(25-27)52-36-26-28(20-22-34(36)44(33)32-14-4-1-11-29(32)43(49)53-44)51-42(48)31-13-3-6-16-38(31)55-57-40-18-8-10-24-46-40/h1-26H
InChi Key
DSMMZTASSIAQPQ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

    $42

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    5 mg

    $105

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    10 mg

    $189

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    Product Description

    WSP-5 is a turn-on fluorescent probe for hydrogen sulfide (H2S).1 Upon reaction with H2S, WSP-5 releases a fluorophore that displays excitation/emission maxima of 502/525 nm, respectively. WSP-5 exhibits a faster turn-on rate and a more sensitive detection limit toward H2S than WSP-1 (Item No. 11179).

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Peng, B., Chen, W., Liu, C., et al. Fluorescent probes based on nucleophilic substitution-cyclization for hydrogen sulfide detection and bioimaging. Chemistry 20(4), 1010-1016 (2014).

    Product Citations

    Zhou, Y., Mazur, F., Liang, K., et al. Sensitivity and selectivity analysis of fluorescent probes for hydrogen sulfide detection. Chem. Asian J. 17(5), e202101399 (2022).

    Jurkowska, H., Wróbel, M., Szlęzak, D., et al. New aspects of antiproliferative activity of 4-hydroxybenzyl isothiocyanate, a natural H2S-donor. Amino Acids 50(6), 699-709 (2018).

    da-Silva, C.J., Mollica, D.C.F., Vicente, M.H., et al. NO, hydrogen sulfide does not come first during tomato response to high salinity. Nitric Oxide (2017).