A red fluorescent dye
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Product Categories

Product Type

Biochemicals
Labeling & Detection
Fluorescent Probes

Research Area

Neuroscience

Application

Fluorescence

Sulforhodamine 101

Item No. 16953

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
9-(2,4-disulfophenyl)-2,3,6,7,12,13,16,17-octahydro-1H,5H,11H,15H-xantheno[2,3,4-ij:5,6,7-i'j']diquinolizin-18-ium, inner salt
CAS Number
60311-02-6
Synonyms
  • SR 101
  • Sulforhodamine 640
Molecular Formula
C31H30N2O7S2
Formula Weight
606.7
Purity
≥95%
Emission
605 nm
Excitation
586 nm
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 25 mg/mlEthanol: 1 mg/mlPBS (pH 7.2): 2 mg/ml
λmax
265, 315, 370, 420, 575 nm
SMILES
OS(C(C=C1S([O-])(=O)=O)=CC=C1C2=C3C(C4=C(N5CCC4)C(CCC5)=C3)=[O+]C6=C(CCC7)C(N7CCC8)=C8C=C62)(=O)=O
InChi Code
InChI=1S/C31H30N2O7S2/c34-41(35,36)20-9-10-21(26(17-20)42(37,38)39)27-24-15-18-5-1-11-32-13-3-7-22(28(18)32)30(24)40-31-23-8-4-14-33-12-2-6-19(29(23)33)16-25(27)31/h9-10,15-17H,1-8,11-14H2,(H-,34,35,36,37,38,39)
InChi Key
COIVODZMVVUETJ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    50 mg

    $49

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    100 mg

    $86

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    250 mg

    $202

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    500 mg

    $329

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    Product Description

    Sulforhodamine 101 is a nonfixable red fluorescent dye (excitation max: 586 nm; emission max: 605 nm) that can be used as a specific marker for astrocytes and an activity-dependent probe for monitoring regulated exocytosis.1 It has been reported to induce long-term potentiation of intrinsic neuronal excitability and a long-lasting increase in evoked excitatory postsynaptic potentials in CA1 pyramidal neurons in hippocampal slices.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Nimmerjahn, A., Kirchhoff, F., Kerr, J.N., et al. Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo. Nat. Methods 1(1), 31-37 (2004).

    2. Kang, J., Kang, N., Yu, Y., et al. Sulforhodamine 101 induces long-term potentiation of intrinsic excitability and synaptic efficacy in hippocampal CA1 pyramidal neurons. Neuroscience 169(4), 1601-1609 (2010).