A FAHFA with anti-diabetic potential
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13-OAHSA

Item No. 17112

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
9Z-octadecenoic acid, 12-carboxy-1-pentyldodecyl ester
CAS Number
1997286-67-5
Molecular Formula
C36H68O4
Formula Weight
564.9
Purity
≥95%
Formulation (Request formulation change)
A 10 mg/ml solution in methyl acetate
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 15 mg/mlEthanol: 20 mg/mlEthanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
SMILES
OC(CCCCCCCCCCCC(OC(CCCCCCC/C=C\CCCCCCCC)=O)CCCCC)=O
InChi Code
InChI=1S/C36H68O4/c1-3-5-7-8-9-10-11-12-13-14-15-19-22-25-29-33-36(39)40-34(30-26-6-4-2)31-27-23-20-17-16-18-21-24-28-32-35(37)38/h12-13,34H,3-11,14-33H2,1-2H3,(H,37,38)/b13-12-
InChi Key
RCTXOTTXFKSGGU-SEYXRHQNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $69

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    5 mg

    $297

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    10 mg

    $525

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    Product Description

    13-OAHSA is a form of FAHFA in which oleic acid is esterified to 13-hydroxy stearic acid. Among the FAHFA family members, OAHSAs are the most abundantly expressed in the serum of glucose tolerant AG4OX mice, which overexpress the Glut4 glucose transporter specifically in adipose tissue.1 As other FAHFAs improve glucose tolerance, stimulate insulin secretion, and have anti-inflammatory effects, 13-OAHSA may be a bioactive lipid with roles in metabolic syndrome and inflammation.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Yore, M.M., Syed, I., Moraes-Vieira, P.M., et al. Discovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects. Cell 159(2), 318-332 (2014).

    Product Citations

    Aryal, P., Syed, I., Lee, J., et al. Distinct biological activities of isomers from several families of branched fatty acid esters of hydroxy fatty acids (FAHFAs). J. Lipid Res. 62, 100108 (2021).