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α-Phthalimidopropiophenone

Item No. 17141

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • α-PAPP
  • 2-Phthalimidopropiophenone
Technical Information
Formal Name
2-(1-methyl-2-oxo-2-phenylethyl)-1H-isoindole-1,3(2H)-dione
CAS Number
19437-20-8
Molecular Formula
C17H13NO3
Formula Weight
279.3
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMF:PBS (pH 7.2) (1:1): 0.5 mg/mlDMSO: 20 mg/mlEthanol: 10 mg/ml
λmax
208, 221, 291 nm
SMILES
O=C(C(C)N1C(C(C=CC=C2)=C2C1=O)=O)C3=CC=CC=C3
InChi Code
InChI=1S/C17H13NO3/c1-11(15(19)12-7-3-2-4-8-12)18-16(20)13-9-5-6-10-14(13)17(18)21/h2-11H,1H3
InChi Key
CKLKGWHINGNHOK-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    α-Phthalimidopropiophenone is a cathinone analog that has been identified in capsules being distributed by the illicit drug market.1 The substitution of the phthalimido moiety for the typical α-amino group may increase the stability of this cathinone in storage. Alternatively, similar nitrogen-protected propiophenones have been shown to be metabolized in vivo to produce cathinone, suggesting that this compound may act as a prodrug.1,2 The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Camilleri, A., Johnston, M.R., Brennan, M., et al. Chemical analysis of four capsules containing the controlled substance analogues 4-methylmethcathinone, 2-fluoromethamphetamine, α-phthalimidopropiophenone and N-ethylcathinone. Forensic Sci. Int. 197(1-3), 59-66 (2010).

    2. Springer, D., Fritschi, G., and Maurer, H.H. Metabolism of the new designer drug α-pyrrolidinoproppiophenone (PPP) and the toxicological detection of PPP and 4'-methyl-α-pyrrolidinopropiophenone (MPPP) studied in rat urine using gas chromatography-mass spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 796(2), 253-266 (2003).