An insecticidal antibiotic
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Milbemycin A4

Item No. 17155

Technical Information
Formal Name
(6R,25R)-5-O-demethyl-28-deoxy-6,28-epoxy-25-ethyl-milbemycin B
CAS Number
51596-11-3
Synonyms
  • Antibiotic B 41A4
  • Milbemycin α3
Molecular Formula
C32H46O7
Formula Weight
Purity
≥85%
A solid
DMF: solubleDMSO: solubleEthanol: solubleMethanol: soluble
SMILES
CC[C@H]([C@@H](C)CC1)O[C@]21C[C@](OC([C@@]3([H])[C@@]4(O)[C@@]5([H])[C@H](O)C(C)=C3)=O)([H])C[C@](C/C=C(C)/C[C@@H](C)/C=C/C=C4\CO5)([H])O2
InChi Code
InChI=1S/C32H46O7/c1-6-27-21(4)12-13-31(39-27)17-25-16-24(38-31)11-10-20(3)14-19(2)8-7-9-23-18-36-29-28(33)22(5)15-26(30(34)37-25)32(23,29)35/h7-10,15,19,21,24-29,33,35H,6,11-14,16-18H2,1-5H3/b8-7+,20-10+,23-9+/t19-,21-,24+,25-,26-,27+,28+,29+,31+,32
InChi Key
VOZIAWLUULBIPN-LRBNAKOISA-N
Origin
Bacterium/Streptomyces hygroscopicus
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    Product Description

    Milbemycin A4 is the prominent member of a complex family of macrocyclic lactones that contain a characteristic spiroketal group produced from the fermentation of soil bacterium S. hygroscopicus subsp. aureolacrimosus.1 As a compound that potentiates glutamate and GABA-gated chloride-channel opening, milbemycin 4 is used as a nematocide and insecticide.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Duke, S.O., Cantrell, C.L., Meepagala, K.M., et alNatural toxins for use in pest management. Toxins (Basel) 2(8), 1943-1962 (2010).