A water-soluble bile pigment
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Bilirubin Conjugate (sodium salt)

Item No. 17170

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2,2'-[(2,17-diethenyl-1,10,11,19,22,23-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-biline-8,12-diyl)bis[(1-oxo-3,1-propanediyl)imino]]bis-ethanesulfonic acid, disodium salt
CAS Number
68683-34-1
Synonyms
  • Bilirubin Ditaurate
Molecular Formula
C37H44N6O10S2• 2Na
Formula Weight
842.9
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 0.25 mg/mlDMSO: 10 mg/mlWater: 5 mg/ml
λmax
210, 452 nm
SMILES
CC1=C(/C=C2NC(C(C=C)=C\2C)=O)NC(CC3=C(CCC(NCCS([O-])(=O)=O)=O)C(C)=C(/C=C4NC(C(C)=C\4C=C)=O)N3)=C1CCC(NCCS([O-])(=O)=O)=O.[Na+].[Na+]
InChi Code
InChI=1S/C37H46N6O10S2.2Na/c1-7-24-23(6)36(46)43-31(24)18-29-22(5)27(10-12-35(45)39-14-16-55(51,52)53)33(41-29)19-32-26(9-11-34(44)38-13-15-54(48,49)50)21(4)28(40-32)17-30-20(3)25(8-2)37(47)42-30;;/h7-8,17-18,40-41H,1-2,9-16,19H2,3-6H3,(H,38,44)(H,39
InChi Key
IQKDYMAMJBFOQJ-MWABKKRNSA-L
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    10 mg

    $41

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    50 mg

    $119

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    100 mg

    $178

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    500 mg

    $775

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    Product Description

    Bilirubin conjugate is a stable, water-soluble ditaurate derivative of bilirubin (Item No. 17161) meant to mimic endogenous bilirubin glucuronide derivatives. In vivo, bilirubin circulates in the plasma and is taken up by hepatocytes and conjugated to one or two glucuronic acids in a reaction catalyzed by UDP glucuronidase to form bilirubin mono or diglucuronide. This water-soluble form is then excreted from the liver in bile in the feces or is converted to urobilinogen and excreted in the urine. In addition to aiding in the disposal of heme, bilirubin and its conjugated derivatives have been shown to exhibit anti-oxidant and antimutagenic effects and to play a role in gut barrier function.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Mölzer, C., Huber, H., Steyrer, A., et al. In vitro antioxidant capacity and antigenotoxic properties of protoporphyrin and structurally related tetrapyrroles. Free Radic. Res. 46(11), 1369-1377 (2012).

    2. Zhou, K., Jiang, M., Liu, Y., et al. Effect of bile pigments on the compromised gut barrier function in a rat model of bile duct ligation. PLoS One 9(6), 1-8 (2014).