A macrolide antibiotic and water-soluble form of erythromycin
Technical Support & Resources

Information provided in the product description is from published literature. Due to the nature of scientific experimentation, your results (e.g., selectivity and effective concentrations) or specific application for this product may differ. If you have questions about how this product fits your application, please contact our technical support staff.

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

Erythromycin lactobionate

Item No. 17189

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-O-β-D-galactopyranosyl-D-gluconate erythromycin
CAS Number
3847-29-8
Molecular Formula
C37H67NO13 • C12H22O12
Formula Weight
1092.2
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
Water: 1 mg/ml
SMILES
C[C@H]1[C@H](O)[C@@](OC)(C)C[C@@](O[C@H]([C@@H](C)C(O[C@H](CC)[C@]([C@H](O)[C@H]2C)(O)C)=O)[C@H](C)[C@@H](O[C@@]3([H])[C@H](O)[C@@H](N(C)C)C[C@@H](C)O3)[C@](C)(O)C[C@@H](C)C2=O)([H])O1.O[C@@H]4[C@H](O)[C@@H](O)[C@H](O[C@]([C@H](O)[C@@H](O)C(O)=O)([H])[C@H](O)CO)O[C@@H]4CO
InChi Code
InChI=1S/C37H67NO13.C12H22O12/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26;13-1-3(15)10(7(18)8(19)11(21)22)24-12-9(20)6(17)5(16)4(2-14)23-12/
InChi Key
NNRXCKZMQLFUPL-WBMZRJHASA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    500 mg

    $36

    Add

    1 g

    $63

    Add

    5 g

    $268

    Add

    10 g

    $469

    Add
    Cayman Chemical
    Neutrophil Biology Wall Poster

    Explore how neutrophils shape the immune response in health and disease. This poster highlights neutrophil pathogen defense mechanisms, including phagocytosis, degranulation, and NETosis, as well as neutrophil roles in inflammation and NET-associated pathologies.

    DOWNLOAD NOW
    Product Description

    Erythromycin lactobionate is a macrolide antibiotic and water-soluble form of erythromycin (Item No. 16486).1 It is active against S. aureus and S. pneumoniae, as well as clinical isolates of group A streptococci (MICs = 0.6, 0.06, and 0.031 µg/ml, respectively).2,3 Erythromycin lactobionate (50 mg/kg) increases survival and reduces the number of lung colony forming units (CFUs) in a mouse model of S. pneumoniae-induced pneumonia.3 It also increases survival in mice infected with P. aeruginosa when administered at doses of 50 and 100 mg/kg.4 Formulations containing erythromycin lactobionate have been used in the treatment of various Gram-positive and Gram-negative bacterial infections.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Periti, P., Mazzei, T., Mini, E., et al. Clinical pharmacokinetic properties of the macrolide antibiotics. Effects of age and various pathophysiological states (Part I). Clin. Pharmacokinet. 16(4), 193-214 (1989).

    2. Lebek, G., and Thöni, G. Effects in vitro of erythromycin, alone and in combination with penicillin, on staphylococci, pneumococci and streptococci. Curr. Med. Res. Opin. 5(2), 3-14 (1978).

    3. Azoulay-Dupuis, E., Bedos, J.P., Vallée, E., et al. Antipneumococcal activity of ciprofloxacin, ofloxacin, and temafloxacin in an experimental mouse pneumonia model at various stages of the disease. J. Infect. Dis. 163(2), 319-324 (1991).

    4. Hirakata, Y., Kaku, M., Tomono, K., et al. Efficacy of erythromycin lactobionate for treating Pseudomonas aeruginosa bacteremia in mice. Antimicrob. Agents Chemother. 36(6), 1198-1203 (1992).