An internal standard for the quantification of 12-OAHSA
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Unlabeled Version(s)
1710812-OAHSA
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12-OAHSA-d17

Item No. 17195

Technical Information
Formal Name
9Z-octadecenoic-11,11',12,12',13,13',14,14',15,15',16,16',17,17',18,18,18-d17 acid, 11-carboxy-1-hexylundecyl ester
CAS Number
2749984-52-7
Molecular Formula
C36H51D17O4
Formula Weight
Purity
≥99% deuterated forms (d1-d17)
Formulation
A 1 mg/ml solution in methyl acetate
DMF: 20 mg/mlDMSO: 15 mg/mlEthanol: 20 mg/mlEthanol:PBS (pH 7.2) (1:1): 0.5 mg/ml
SMILES
OC(CCCCCCCCCCC(OC(CCCCCCC/C=C\C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])[2H])=O)CCCCCC)=O
InChi Code
InChI=1S/C36H68O4/c1-3-5-7-9-10-11-12-13-14-15-16-17-22-25-29-33-36(39)40-34(30-26-8-6-4-2)31-27-23-20-18-19-21-24-28-32-35(37)38/h13-14,34H,3-12,15-33H2,1-2H3,(H,37,38)/b14-13-/i1D3,3D2,5D2,7D2,9D2,10D2,11D2,12D2
InChi Key
OCHJVQODRYVDAA-QVXTUTMISA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    12-OAHSA-d17 is intended for use as an internal standard for the quantification of 12-OAHSA (Item No. 17108) by GC- or LC-mass spectrometry. Branched fatty acid esters of hydroxy fatty acids (FAHFAs) are newly identified endogenous lipids regulated by fasting and high-fat feeding and associated with insulin sensitivity.1 Structurally, these esters are comprised of a C-16 or C-18 fatty acid (e.g., palmitoleic, palmitic, oleic, or stearic acid) linked to either a C-16 or C-18 hydroxy substituent. 12-OAHSA is a FAHFA in which oleic acid is esterified at the 12th carbon of hydroxy stearic acid. Among the FAHFA family members, OAHSAs are the most abundantly expressed in the serum of glucose tolerant AG4OX mice, which overexpress the Glut4 glucose transporter specifically in adipose tissue.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Yore, M.M., Syed, I., Moraes-Vieira, P.M., et alDiscovery of a class of endogenous mammalian lipids with anti-diabetic and anti-inflammatory effects. Cell 159(2), 318-332 (2014).