An inactive analog of PD 150606
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PD 145305

Item No. 17261

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
α-mercapto-benzenepropanoic acid
CAS Number
90536-15-5
Molecular Formula
C9H10O2S
Formula Weight
182.2
Purity
≥95%
Formulation
A solution in ethanol
Solubility(Learn about Variance in Solubility)
DMF: 20 mg/mlDMSO: 20 mg/mlEthanol: 20 mg/mlPBS (pH 7.2): 0.3 mg/ml
SMILES
OC(C(S)CC1=CC=CC=C1)=O
InChi Code
InChI=1S/C9H10O2S/c10-9(11)8(12)6-7-4-2-1-3-5-7/h1-5,8,12H,6H2,(H,10,11)
InChi Key
HGIOOMCLOWLFTJ-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $48

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    5 mg

    $206

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    10 mg

    $366

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    Product Description

    PD 145305 is an inactive analog of PD 150606 (Item No. 13859), a selective inhibitor of calpains (Kis = 0.21 and 0.37 µM for µ- and m-calpain, respectively).1 It is inactive at concentrations up to 500 µM.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wang, K.K.W., Nath, R., Posner, A., et al. An alpha-mercaptoacrylic acid derivative is a selective nonpeptide cell-permeable calpain inhibitor and is neuroprotective. Proc. Natl. Acad. Sci. USA 93, 6687-6692 (1996).