A redox-sensitive probe
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Tetrazolium (chloride)

Item No. 17342

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2,3,5-triphenyl-2H-tetrazolium, monochloride
CAS Number
298-96-4
Synonyms
  • Tetrazolium Red
  • 2,3,5-Triphenyl Tetrazolium Chloride
  • TTC
Molecular Formula
C19H15N4 • Cl
Formula Weight
334.8
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMSO: 0.25 mg/mlEthanol: 1 mg/mlPBS (pH 7.2): 1 mg/ml
λmax
247 nm
SMILES
C1([N+]2=NC(C3=CC=CC=C3)=NN2C4=CC=CC=C4)=CC=CC=C1.[Cl-]
InChi Code
InChI=1S/C19H15N4.ClH/c1-4-10-16(11-5-1)19-20-22(17-12-6-2-7-13-17)23(21-19)18-14-8-3-9-15-18;/h1-15H;1H/q+1;/p-1
InChi Key
PKDBCJSWQUOKDO-UHFFFAOYSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 g

    $36

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    10 g

    $49

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    25 g

    $103

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    50 g

    $161

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    Product Description

    TTC is a redox indicator used to detect cellular respiration.1 It is primarily reduced by Complex I in mitochondria and, under anaerobic conditions, is completely reduced to an insoluble red 1,3,5-triphenylformazan.2 TTC assays are typically used as a mitochondrial redox potential indicator for cell death.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Sabnis, R.W. Handbook of biological dyes and stains: Synthesis and industrial applications. (2010).

    2. Berridge, M.V., Tan, A.S., and Herst, P.M. Tetrazolium dyes as tools in cell biology: New insights into their cellular reduction. Biotechnol. Ann. Rev. 11, 127-152 (2005).