A cephalosporin antibiotic
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Active Metabolite(s)
27578Desacetyl Cefapirin (sodium salt)
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Cefapirin

Item No. 17406

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(6R,7R)-3-[(acetyloxy)methyl]-8-oxo-7-[[(4-pyridinylthio)acetyl]amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CAS Number
21593-23-7
Synonyms
  • Cefadyl
  • Cephapirin
Molecular Formula
C17H17N3O6S2
Formula Weight
423.5
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 5 mg/mlDMSO: 10 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
261 nm
SMILES
O=C(N[C@@H]1C(N2[C@]1([H])SCC(COC(C)=O)=C2C(O)=O)=O)CSC3=CC=NC=C3
InChi Code
InChI=1S/C17H17N3O6S2/c1-9(21)26-6-10-7-28-16-13(15(23)20(16)14(10)17(24)25)19-12(22)8-27-11-2-4-18-5-3-11/h2-5,13,16H,6-8H2,1H3,(H,19,22)(H,24,25)/t13-,16-/m1/s1
InChi Key
UQLLWWBDSUHNEB-CZUORRHYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 mg

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    Cayman Chemical
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    Product Description

    Cefapirin is a first generation cephalosporin antibiotic that is broadly effective against gram-negative and gram-positive bacteria.1,2 The bactericidal action of cefapirin results from inhibition of cell-wall synthesis, mediated by its binding to penicillin binding proteins. It is mainly used in veterinary medicine for intramammary treatment of mastitis and intrauterine treatment of endometritis in cattle.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1.  Committee for veterinary medicinal products: Cefapririn. EMEA, 1-6 (2001).

    2. Ray, P., Knowlton, K.F., Shang, C., et al. Development and validation of a UPLC-MS/MS method to monitor cephapirin excretion in dairy cows following intramammary infusion. PLoS One 9(11), 1-12 (2014).