An alkyl glyceryl ether
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1-O-Dodecyl-rac-glycerol

Item No. 17441

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
3-(dodecyloxy)-1,2-propanediol
CAS Number
1561-07-5
Synonyms
  • 2,3-Dihydroxypropyl dodecyl ether
  • DDG
  • 1-O-Lauryl-rac-glycerol
  • Lauryl glyceryl ether
  • MG(O-12:0/0:0/0:0)
  • NSC 38645
Molecular Formula
C15H32O3
Formula Weight
260.4
Purity
≥95%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
Methanol: Soluble
SMILES
OC(CO)COCCCCCCCCCCCC
InChi Code
InChI=1S/C15H32O3/c1-2-3-4-5-6-7-8-9-10-11-12-18-14-15(17)13-16/h15-17H,2-14H2,1H3
InChi Key
GBXRUYNQDDTQQS-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    500 mg

    $109

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    1 g

    $207

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    Product Description

    1-O-Dodecyl-rac-glycerol is an alkyl glyceryl ether. It is also a nonionic surfactant.1 1-O-Dodecyl-rac-glycerol increases autolysin activity in S. faecium and inhibits peptidoglycan synthesis in S. mutans.2 It induces mouse peritoneal macrophage activation ex vivo when administered at a dose of 100 ng/animal.3 1-O-Dodecyl-rac-glycerol (4 and 8 mg/animal) increases survival in an Ehrlich murine ascites tumor model.4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. de Paula, F.H.M., de Freitas, F.A., Nunes, D.G., et al. Alkyl glyceryl ethers as water-based lubricant additives in mixtures with xanthan gum. Colloids and Surfaces A: Physicochemical and Engineering Aspects 634, 127881 (2022).

    2. Ved, H.S., Gustow, E., and Pieringer, R.A. Inhibition of peptidoglycan synthesis of Streptococcus faecium ATCC 9790 and Streptococcus mutans BHT by the antibacterial agent dodecyl glycerol. Biosci. Rep. 4(8), 659-664 (1984).

    3. Yamamoto, N., St. Claire, D.A., Homma, S., et al. Activation of mouse macrophages by alkylglycerols, inflammation products of cancerous tissues. Cancer Res. 48(21), 6044-6049 (1988).

    4. Ando, K., Kodama, K., Kato, A., et al. Antitumor activity of glyceryl ethers. Cancer Res. 32(1), 125-129 (1972).