A zwitterionic non-detergent sulfobetaine
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Product Type

Biochemicals
Lab Reagents

NDSB-256-4T

Item No. 17443

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-(1,1-dimethylethyl)-1-(3-sulfopropyl)-pyridinium, inner salt
CAS Number
570412-84-9
Molecular Formula
C12H19NO3S
Formula Weight
257.3
Purity
≥98%
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Sparingly soluble: 1-10 mg/mlEthanol: Sparingly soluble: 1-10 mg/mlPBS (pH 7.2): Sparingly soluble: 1-10 mg/ml
SMILES
[O-]S(CCC[N+]1=CC=C(C(C)(C)C)C=C1)(=O)=O
InChi Code
InChI=1S/C12H19NO3S/c1-12(2,3)11-5-8-13(9-6-11)7-4-10-17(14,15)16/h5-6,8-9H,4,7,10H2,1-3H3
InChi Key
QMGYGZCGWOKPGR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    1 g

    $33

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    5 g

    $158

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    10 g

    $297

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    Product Description

    NDSB-256-4T is a zwitterionic non-detergent sulfobetaine (NDSB).1 It improves the renaturation yield of unfolded hen lysozyme or the unfolded β2 subunit of E. coli tryptophan synthase when used at concentrations of 0.6 and 1 M, respectively, in renaturation buffer.2 NDSB-256-4T (0.2 mg/ml) enhances electron extraction and transport, improves interfacial contact, and increases power conversion efficiency when used to modify the tin oxide electron transport layer in inverted organic solar cells.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Frederickson, M., Vuillard, L., and Abell, C. Novel selenium containing non-detergent sulphobetaines. Tetrahedron Lett. 44, 7925-7928 (2003).

    2. Expert-Bezançon, N., Rabilloud, T., Vuillard, L., et al. Physical–chemical features of non-detergent sulfobetaines active as protein-folding helpers. Biophys. Chem. 100(1-3), 469-479 (2003).

    3. Tran, V.-H., Kim, S.-K., and Lee, S.-H. Zwitterion nondetergent sulfobetaine-modified SnO2 as an efficient electron transport layer for inverted organic solar cells. ACS Omega 4(21), 19225-19237 (2019).