An antiproliferative fatty acid amide
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(S)-α-Methylbenzyl Ricinoleamide

Item No. 17546

Technical Information
Formal Name
12R-hydroxy-N-[(1S)-1-phenylethyl]-9Z-octadecenamide
CAS Number
1246776-22-6
Molecular Formula
C26H43NO2
Formula Weight
Purity
≥98%
A 10 mg/ml solution in ethanol
DMF: 30 mg/mlDMSO: 25 mg/mlEthanol: 30 mg/mlEthanol:PBS (pH 7.2) (1:3): 0.25 mg/ml
SMILES
O=C(N[C@@H](C)C1=CC=CC=C1)CCCCCCC/C=C\C[C@H](O)CCCCCC
InChi Code
InChI=1S/C26H43NO2/c1-3-4-5-15-20-25(28)21-16-10-8-6-7-9-11-17-22-26(29)27-23(2)24-18-13-12-14-19-24/h10,12-14,16,18-19,23,25,28H,3-9,11,15,17,20-22H2,1-2H3,(H,27,29)/b16-10-/t23-,25+/m0/s1
InChi Key
SIPLDWKCFLEICO-UPGFSEOHSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    Product Description

    (S)-α-Methylbenzyl ricinoleamide is a fatty acid amide derived from ricinoleic acid and methyl benzylamine.1 It demonstrates potent growth inhibition of glioma (U251), breast (MCF-7), ovarian (NCI-ADR/RES and OVCAR-3), kidney (786-0), non-small cell lung (NCI-H460), and prostate (PC-3) cancer cells with a mean GI50 value of 6.9 µM.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. dos Santos, D.S., Piovesan, L.A., D'Oca, C.R.M., et alAntiproliferative activity of synthetic fatty acid amides from renewable resources. Bioorg. Med. Chem. 23(2), 340-347 (2015).