A diuretic
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5-chloro Hydrochlorothiazide

Item No. 17571

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5,6-dichloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide, 1,1-dioxide
CAS Number
5233-42-1
Molecular Formula
C7H7Cl2N3O4S2
Formula Weight
332.2
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMF:PBS(pH 7.2)(1:1): 0.5 mg/mlDMSO: 20 mg/ml
λmax
230, 272 nm
SMILES
O=S1(C2=CC(S(N)(=O)=O)=C(Cl)C(Cl)=C2NCN1)=O
InChi Code
InChI=1S/C7H7Cl2N3O4S2/c8-5-3(17(10,13)14)1-4-7(6(5)9)11-2-12-18(4,15)16/h1,11-12H,2H2,(H2,10,13,14)
InChi Key
BSNKBIJVLZUERH-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    1 mg

    $90

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    5 mg

    $370

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    10 mg

    $696

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    Product Description

    5-chloro Hydrochlorothiazide is a derivative of hydrochlorothiazide, which is a diuretic and antihypertensive agent that increases renal excretion of sodium, potassium, chloride, and bicarbonate ions by inhibiting tubular reabsorptive mechanisms.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Laragh, J.H. The mode of action and use of chlorothiazide and related compounds. Circulation 26, 121-132 (1962).

    2. Nath, M.R., and Saira, M. Synthesis, isolation, and characterization of hydrochlorothiazide dimer impurity. J. Pharm. Sci. 5(Suppl 3), 867-871 (2013).