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MMDA-2 (hydrochloride)

Item No. 17659

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • MMDA 2-methoxy analog​
Technical Information
Formal Name
6-methoxy-α-methyl-1,3-benzodioxole-5-ethanamine, monohydrochloride
CAS Number
64778-82-1
Molecular Formula
C11H15NO3 • HCl
Formula Weight
245.7
Purity
≥95%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 30 mg/mlDMSO: 30 mg/mlEthanol: 10 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
238, 300 nm
SMILES
NC(C)CC1=C(OC)C=C(OCO2)C2=C1.Cl
InChi Code
InChI=1S/C11H15NO3.ClH/c1-7(12)3-8-4-10-11(15-6-14-10)5-9(8)13-2;/h4-5,7H,3,6,12H2,1-2H3;1H
InChi Key
ZGJVMWNBNRUVHR-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    MMDA-2 (hydrochloride) (Item No. 17659) is an analytical reference standard that is classified as an amphetamine. It only weakly induces the release of serotonin or dopamine from rat brain synaptosomes and does not produce amphetamine-like responses in drug discrimination studies in rats.1,2 Instead, MMDA-2 is thought to act as a 5-HT2A agonist, which may account for hallucinogenic effects.3 This product is intended for forensic and research applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. McKenna, D.J., Guan, X.M., and Shulgin, A.T. 3,4-Methylenedioxyamphetamine (MDA) analogues exhibit differential effects on synaptosomal release of 3H-dopamine and 3H-5-hydroxytryptamine. Pharmacol. Biochem. Behav. 38(3), 505-512 (1991).

    2. Glennon, R.A., Yousif, M., Naiman, N., et al. Methcathinone: A new and potent amphetamine-like agent. Pharmacol. Biochem. Behav. 26(3), 547-551 (1987).

    3. Clare, B.W. QSAR of benzene derivatives: Comparison of classical descriptors, quantum theoretic parameters and flip regression, exemplified by phenylalkylamine hallucinogens. J.Comput.Aided Mol.Des. 16(8-9), 611-633 (2002).