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Aniracetam

Item No. 17752

Product Insert (PDF)GC-MS (PDF)Safety Data Sheet (SDS) (PDF)
Synonyms
Synonyms
  • Memodrin
  • Ro 13-5057
  • Sarpul
Technical Information
Formal Name
1-(4-methoxybenzoyl)-2-pyrrolidinone
CAS Number
72432-10-1
Molecular Formula
C12H13NO3
Formula Weight
219.2
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMF:PBS(pH 7.2)(1:1): 0.5 mg/mlDMSO: 20 mg/mlEthanol: 5 mg/ml
λmax
218, 281 nm
SMILES
COC1=CC=C(C(N2CCCC2=O)=O)C=C1
InChi Code
InChI=1S/C12H13NO3/c1-16-10-6-4-9(5-7-10)12(15)13-8-2-3-11(13)14/h4-7H,2-3,8H2,1H3
InChi Key
ZXNRTKGTQJPIJK-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Aniracetam (Item No. 17752) is an analytical reference standard that is classified as a nootropic. It can block AMPA receptor desensitization and, consequently, enhance excitatory activity by several fold.1,2 It can also allosterically modulate metabotropic glutamate receptors.3 The therapeutic value of aniracetam has been explored in various rodent models for the treatment of cognitive impairment or other CNS disorders.3 This product is intended for forensic and research purposes only.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bräuner-Osborne, H., Egebjerg, J., Nielsen, E.O., et al. Ligands for glutamate receptors: Design and therapeutic prospects. J. Med. Chem. 43(14), 2609-2645 (2000).

    2. Lawrence, J.J., Brenowitz, S., and Trussell, L.O. The mechanism of action of aniracetam at synaptic α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors: Indirect and direct effects on desensitization. Mol. Pharmacol. 64(2), 269-278 (2003).

    3. Nakamura, K. Aniracetam: Its novel therapeutic potential in cerebral dysfunctional disorders based on recent pharmacological discoveries. CNS Drug Rev. 8(1), 70-89 (2002).