An α2-adrenoceptor agonist
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Analytical Standard(s)
38583Detomidine (hydrochloride)
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Detomidine (hydrochloride)

Item No. 17853

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5-[(2,3-dimethylphenyl)methyl]-1H-imidazole, monohydrochloride
CAS Number
90038-01-0
Synonyms
  • MPV 253AII
Molecular Formula
C12H14N2 • HCl
Formula Weight
222.7
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMSO: 25 mg/mlEthanol: 30 mg/mlPBS (pH 7.2): 1 mg/ml
λmax
213 nm
SMILES
CC1=C(C)C(CC2=CNC=N2)=CC=C1.Cl
InChi Code
InChI=1S/C12H14N2.ClH/c1-9-4-3-5-11(10(9)2)6-12-7-13-8-14-12;/h3-5,7-8H,6H2,1-2H3,(H,13,14);1H
InChi Key
OIWRDXKNDCJZSM-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    50 mg

    $123

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    100 mg

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    250 mg

    $399

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    Product Description

    Detomidine is a selective α2-adrenoceptor agonist (Ki = 1.62 nM) that binds to α1-adrenoceptors with much weaker potency (Ki = 415 nM).1 Formulations containing detomidine have been used as veterinary sedatives.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Virtanen, R., Savola, J.M., Saano, V., et al. Characterization of the selectivity, specificity and potency of medetomidine as an α2-adrenoceptor agonist. Eur. J. Pharmacol. 150(1-2), 9-14 (1988).