An echinocandin antifungal
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Micafungin (sodium salt)

Item No. 18009

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-[(4R,5R)-4,5-dihydroxy-N2-[4-[5-[4-(pentyloxy)phenyl]-3-isoxazolyl]benzoyl]-L-ornithine]-4-[(4S)-4-hydroxy-4-[4-hydroxy-3-(sulfooxy)phenyl]-L-threonine]-pneumocandin A0, monosodium salt
CAS Number
208538-73-2
Synonyms
  • FK463
  • Mycamine
Molecular Formula
C56H71N9O23S • Na
Formula Weight
1293.3
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 10 mg/mlPBS (pH 7.2): 1 mg/ml
λmax
270 nm
SMILES
O=C([C@](NC1=O)([H])[C@@H]([C@@H](O)C2=CC(OS(O)(=O)=O)=C(C=C2)O)O)N[C@]([H])(C(N3[C@@]([H])([C@H]([C@@H](C)C3)O)C(N[C@@H]([C@@H](C[C@@H](C(N[C@@](C(N4[C@]1(C[C@H](C4)O)[H])=O)([H])[C@@H](C)O)=O)NC(C5=CC=C(C6=NOC(C7=CC=C(OCCCCC)C=C7)=C6)C=C5)=O)O)O)=O
InChi Code
InChI=1S/C56H71N9O23S.Na/c1-4-5-6-17-86-32-14-11-28(12-15-32)39-21-33(63-87-39)27-7-9-29(10-8-27)49(75)58-34-20-38(70)52(78)62-54(80)45-46(72)25(2)23-65(45)56(82)43(37(69)22-41(57)71)60-53(79)44(48(74)47(73)30-13-16-36(68)40(18-30)88-89(83,84)85)61-5
InChi Key
PWAXVQURCGJSNE-WZPXRXMFSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $36

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    5 mg

    $120

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    10 mg

    $203

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    25 mg

    $420

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    Product Description

    Micafungin is an echinocandin antifungal that inhibits 1,3-β-D-glucan synthesis.1,2 It has fungicidal activity against virtually all species of Candida, including those resistant to fluconazole, and is fungistatic against Aspergillus spp.3,4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Bormann, A.M., and Morrison, V.A. Review of the pharmacology and clinical studies of micafungin. Drug. Des. Devel. Ther. 3, 295-302 (2009).

    2. Carillo-Muñoz, A.J., Giusiano, G., Ezkurra, P.A., et al. Antifungal agents: mode of action in yeast cells. Rev.Esp.Quimioter. 19(2), 130-139 (2006).

    3. Pfaller, M.A., Boyken, L., Hollis, R.J., et al. In vitro susceptibility of clinical isolates of Aspergillus spp. to anidulafungin, caspofungin, and micafungin: A head-to-head comparison using the CLSI M38-A2 broth microdilution method. J. Clin. Microbiol. 47(10), 3323-3325 (2009).

    4. Vehreschild, J.J., and Cornely, O.A. Micafungin sodium, the second of the echinocandin class of antifungals: Theory and practice. Future Microbiol. 1(2), 161-170 (2006).