An allosteric inhibitor of PRMT3
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UNC2327

Item No. 18122

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-1,2,3-benzothiadiazol-6-yl-N'-[2-oxo-2-(1-piperidinyl)ethyl]-urea
CAS Number
1426152-53-5
Molecular Formula
C14H17N5O2S
Formula Weight
319.4
Purity
≥98%
Formulation
A solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMF: Soluble: 10 mg/mLDMSO: 2 mg/mlDMSO: Soluble: 2 mg/mL
λmax
222, 256, 311 nm
SMILES
O=C(CNC(NC1=CC=C(N=NS2)C2=C1)=O)N3CCCCC3
InChi Code
InChI=1S/C14H17N5O2S/c20-13(19-6-2-1-3-7-19)9-15-14(21)16-10-4-5-11-12(8-10)22-18-17-11/h4-5,8H,1-3,6-7,9H2,(H2,15,16,21)
InChi Key
MYTRGTBDVGKKRO-UHFFFAOYSA-N
Shipping & Storage Information
Storage
Room temperature
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $52

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    5 mg

    $189

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    10 mg

    $275

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    25 mg

    $621

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    Product Description

    UNC2327 is an allosteric inhibitor of protein arginine methyltransferase 3 (PRMT3; IC50 = 230 nM).1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Liu, F., Li, F., Ma, A., et al. Exploiting an allosteric binding site of PRMT3 yields potent and selective inhibitors. J. Med. Chem. 56(5), 2110-2124 (2013).