A specific adenosine A2 receptor agonist
Technical Support & Resources

Visit our FAQ

Contact Us

Toll Free Phone (USA and Canada Only): (888) 526-5351
Direct Phone: (734) 975-3888

Request Technical Support

Technical Support Request

To streamline the process attach the appropriate questionnaire to your inquiry.

Download IHC QuestionnaireDownload WB Questionnaire

View Our Privacy Statement for details on how we use and protect your data. In addition, this site is protected by hCaptcha and its Privacy Policy and Terms of Service apply.

5'-(N-Cyclopropyl)carboxamidoadenosine

Item No. 18157

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
1-(6-amino-9H-purin-9-yl)-N-cyclopropyl-1-deoxy-β-D-ribofuranuronamide
CAS Number
50908-62-8
Synonyms
  • CPCA
Molecular Formula
C13H16N6O4
Formula Weight
320.3
Purity
≥95%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMSO: 14 mg/mlEthanol: 2 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
259 nm
SMILES
O[C@H]1[C@H](N2C=NC3=C2N=CN=C3N)O[C@H](C(NC4CC4)=O)[C@H]1O
InChi Code
InChI=1S/C13H16N6O4/c14-10-6-11(16-3-15-10)19(4-17-6)13-8(21)7(20)9(23-13)12(22)18-5-1-2-5/h3-5,7-9,13,20-21H,1-2H2,(H,18,22)(H2,14,15,16)/t7-,8+,9-,13+/m0/s1
InChi Key
MYNRELUCFAQMFC-QRIDJOKKSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Recommended Products

Certificates of Analysis & Batch Specific Data

Provide batch numbers separated by commas to download or request available product inserts, QC sheets, certificates of analysis, data packs, and GC-MS data.

Download most recent Certificate of Analysis for this product

    5 mg

    $55

    Add

    10 mg

    $104

    Add

    25 mg

    $190

    Add

    50 mg

    $349

    Add
    Product Description

    5'-(N-Cyclopropyl)carboxamidoadenosine is a specific adenosine A2 receptor agonist with antipyretic and anticonvulsant activity.1,2 It stimulates the production of cyclic AMP in CHO-K1 cells with an EC50 value of 5.3 µM.3

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Gagalo, I.T., and Matuszek, M.T. The effect of N6-cyclohexyladenosine and 5'-(N-cyclopropyl)-carboxamidoadenosine on pyrogen fever in rabbits. Ann. N. Y. Acad. Sci. 813(1), 353-359 (1997).

    2. Huber, A., Güttinger, M., Möhler, H., et al. Seizure suppression by adenosine A2A receptor activation in a rat model of audiogenic brainstem epilepsy. Neurosci. Lett. 329, 289-292 (2002).

    3. de Zwart, M., Link, R., von Frijtag Drabbe Künzel, J.K., et al. A functional screening of adenosine analogues at the adenosine A2B receptor: a search for potent agonists. Nucleosides Nucleotides 17(6), 969-985 (1998).