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4-acetoxy DET (hydrochloride)

Item No. 18171

Synonyms
Synonyms
  • 4-acetoxy-N,N-Diethyltryptamine
  • Ethacetin
  • Ethylacybin
Technical Information
Formal Name
3-[2-(diethylamino)ethyl]-1H-indol-4-ol 4-acetate, monohydrochloride
CAS Number
2749504-15-0
Molecular Formula
C16H22N2O2 • HCl
Formula Weight
Purity
≥98%
Formulation
A crystalline solid
DMF: 30 mg/mlDMSO: 10 mg/mlEthanol: 20 mg/mlMethanol: 1 mg/mlPBS (pH 7.2): 10 mg/ml
λmax
220, 277 nm
SMILES
CCN(CC)CCC1=CNC2=CC=CC(OC(C)=O)=C21.Cl
InChi Code
InChI=1S/C16H22N2O2.ClH/c1-4-18(5-2)10-9-13-11-17-14-7-6-8-15(16(13)14)20-12(3)19;/h6-8,11,17H,4-5,9-10H2,1-3H3;1H
InChi Key
DLUXGDNEKOMIDY-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Derivatives of N,N-diethyltryptamine (DET) are hallucinogenic compounds with activity at the serotonin (5-hydroxytryptamine) receptors.1 4-acetoxy DET (hydrochloride) (Item No. 18171) is an analytical reference standard categorized as a tryptamine.2 4-acetoxy DET induces the head-twitch response (HTR) in mice, indicating hallucinogenic potential. This product is intended for research and forensic applications.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Blair, J.B., Kurrasch-Orbaugh, D., Marona-Lewicka, D., et alEffect of ring fluorination on the pharmacology of hallucinogenic tryptamines. J. Med. Chem. 43(24), 4701-4710 (2000).

    2. Klein, A.K., Chatha, M., Laskowski, L.J., et alInvestigation of the structure−activity relationships of psilocybin analogues. ACS Pharmacol. Transl. Sci. 4(2), 533-542 (2020).

    Product Citations

    Kozell, L.B., Eshleman, A.J., Swanson, T.L., et alPharmacologic activity of substituted tryptamines at 5-HT2AR, 5-HT2CR, 5-HT1AR, and SERT. J. Pharmacol. Exp. Ther. JPET-AR-2022-001454 (2023).

    Gatch, M.B., Hoch, A., and Carbonaro, T.M. Discriminative stimulus effects of substituted tryptamines in rats. ACS Pharmacol. Transl. Sci. 4(2), 467-471 (2020).