A metabolite of DHA
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(±)13(14)-DiHDPA

Item No. 18175

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
13,14-dihydroxy-4Z,7Z,10Z,16Z,19Z-docosapentaenoic acid
CAS Number
1345275-24-2
Synonyms
  • 13(14)-DiHDPA
  • 13(14)-DiHDoPE
  • 13,14-DiHDPE
Molecular Formula
C22H34O4
Formula Weight
362.5
Purity
≥98%
Formulation (Request formulation change)
A 100 µg/ml solution in ethanol
Solubility(Learn about Variance in Solubility)
DMF: 50 mg/mlDMSO: 50 mg/mlEthanol: 50 mg/mlPBS (pH 7.2): 0.25 mg/ml
SMILES
CC/C=C\C/C=C\C[C@@H](O)[C@H](O)C/C=C\C/C=C\C/C=C\CCC(O)=O
InChi Code
InChI=1S/C22H34O4/c1-2-3-4-5-11-14-17-20(23)21(24)18-15-12-9-7-6-8-10-13-16-19-22(25)26/h3-4,6-7,10-15,20-21,23-24H,2,5,8-9,16-19H2,1H3,(H,25,26)/b4-3-,7-6-,13-10-,14-11-,15-12-/t20-,21-/m1/s1
InChi Key
LINXWSBRRJSWHL-QBEJVNRSSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    50 µg

    $94

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    100 µg

    $160

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    500 µg

    $655

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    1 mg

    $1,029

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    Product Description

    (±)13(14)-DiHDPA is a metabolite of docosahexaenoic acid (DHA; Item No. 90310) that is produced via oxidation by cytochrome P450 epoxygenases.1 Epoxygenase metabolites of DHA, including (±)13(14)-DiHDPA, are reported to inhibit angiogenesis, tumor growth, and metastasis.2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. VanRollins, M., Baker, R.C., Sprecher, H., et al. Oxidation of docosahexaenoic acid by rat liver microsomes. The Journal of Biological Chemisty 259(9), 5776-5783 (1984).

    2. Zhang, G., Panigrahy, D., Mahakian, L.M., et al. Epoxy metabolites of docosahexaenoic acid (DHA) inhibit angiogenesis, tumor growth, and metastasis. Proc. Natl. Acad. Sci. USA 110(16), 6530-6535 (2013).