An internal standard for the quantification of acetaminophen
Related Products
Alternative(s)
22645Acetaminophen-d4
Analytical Standard(s)
22646Acetaminophen-d4 (CRM)
Unlabeled Version(s)
10024Acetaminophen
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Acetaminophen-d4

Item No. 18245

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
N-(4-hydroxyphenyl-2,3,5,6-d4)-acetamide
CAS Number
64315-36-2
Synonyms
  • 4-Acetamidophenol-d4
  • APAP-d4
  • 4'-Hydroxyacetanilide-d4
Molecular Formula
C8H5D4NO2
Formula Weight
155.2
Purity
≥99% deuterated forms (d1-d4)
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 25 mg/mlDMSO: 20 mg/mlEthanol: 25 mg/mlPBS (pH 7.2): 2 mg/ml
λmax
249 nm
SMILES
OC1=C([2H])C([2H])=C(NC(C)=O)C([2H])=C1[2H]
InChi Code
InChI=1S/C8H9NO2/c1-6(10)9-7-2-4-8(11)5-3-7/h2-5,11H,1H3,(H,9,10)/i2D,3D,4D,5D
InChi Key
RZVAJINKPMORJF-QFFDRWTDSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    5 mg

    $90

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    10 mg

    $168

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    25 mg

    $392

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    50 mg

    $696

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    Product Description

    Acetaminophen-d4 is intended for use as an internal standard for the quantification of acetaminophen (Item No. 10024 | 22629) by GC- or LC-MS. Acetaminophen is an analgesic and antipyretic compound that inhibits COX-2 activity by more than 80%, albeit at relatively high doses, while it is less effective against COX-1.1 Acetaminophen-d4 is also available as an analytical reference standard (Item No. 22645)

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Hinz, B., Cheremina, O., and Brune, K. Acetaminophen (paracetamol) is a selective cyclooxygenase-2- inhibitor in man. The FASEB Journal 22(2), 383-390 (2007).