A potent vasodilator and inhibitor of platelet aggregation
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Prostaglandin I3 (sodium salt)

Item No. 18300

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
6,9α-epoxy-11α,15S-dihydroxy-prosta-5Z,13E,17Z-trien-1-oic acid, monosodium salt
CAS Number
68324-96-9
Synonyms
  • PGI3
Molecular Formula
C20H29O5 • Na
Formula Weight
372.4
Purity
≥95%
Formulation
A lyophilized powder
Solubility(Learn about Variance in Solubility)
PBS (pH >10.2): 10 mg/ml
SMILES
O[C@H]1[C@H](/C=C/[C@@H](O)C/C=C\CC)[C@@H](C/C(O2)=C/CCCC([O-])=O)[C@@H]2C1.[Na+]
InChi Code
InChI=1S/C20H30O5.Na/c1-2-3-4-7-14(21)10-11-16-17-12-15(8-5-6-9-20(23)24)25-19(17)13-18(16)22;/h3-4,8,10-11,14,16-19,21-22H,2,5-7,9,12-13H2,1H3,(H,23,24);/q;+1/p-1/b4-3-,11-10+,15-8-;/t14-,16+,17+,18+,19-;/m0./s1
InChi Key
JYCZBBNTGSRZMY-YICKWJRGSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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Certificates of Analysis & Batch Specific Data

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    50 µg

    $107

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    100 µg

    $203

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    500 µg

    $854

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    1 mg

    $1,067

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    Product Description

    PGI3 is synthesized from EPA by COX and PGI synthase. PGI3 has a short in vivo half-life and is hydrolyzed to Δ17-6-keto PGF1α. The platelet and vascular activity of PGI3 is equivalent to that of PGI2.1,2

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Mann, N.J., Warrick, G.E., O'Dea, K., et al. The effect of linoleic, arachidonic, and eicosapentaenoic acid supplementation of prostacyclin production in rats. Lipids 29(3), 157-162 (1994).

    2. Johnson, R.A., Lincoln, F.H., Nidy, E.G., et al. Synthesis and characterization of prostacyclin, 6-ketoprostaglandin F1α, prostaglandin I1, and prostaglandin I3. J. Am. Chem. Soc. 100(24), 7690-7704 (1978).