A biotinylation reagent
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Biotin hydrazide

Item No. 18418

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoic acid hydrazide
CAS Number
66640-86-6
Molecular Formula
C10H18N4O2S
Formula Weight
258.3
Purity
≥95%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMSO: 5 mg/mlDMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml
SMILES
NNC(CCCC[C@@H]1SC[C@@](N2)([H])[C@]1([H])NC2=O)=O
InChi Code
InChI=1S/C10H18N4O2S/c11-14-8(15)4-2-1-3-7-9-6(5-17-7)12-10(16)13-9/h6-7,9H,1-5,11H2,(H,14,15)(H2,12,13,16)/t6-,7-,9-/m0/s1
InChi Key
KOZWHQPRAOJMBN-ZKWXMUAHSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    100 mg

    $63

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    250 mg

    $123

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    500 mg

    $213

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    1 g

    $363

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    Product Description

    Biotin hydrazide is a biotinyl derivative used to label surface functional groups, antibodies, lectins, sugars, nucleic acids, or molecules with free carboxylic or keto groups.1 Biotin hydrazide is used as a probe for determining protein carbonylation, an irreversible posttranslational modification resulting from the actions of reactive oxygen species or lipid oxidation products.2 The reaction of this probe is direct and does not require catalysts or reducing agents.

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Diamandis, E.P., and Christopoulos, T.K. The biotin-(strept)avidin system: Principles and applications in biotechnology. Clin. Chem. 37(5), 625-636 (1991).

    2. Madian, A.G., and Regnier, F.E. Proteomic identification of carbonylated proteins and their oxidation sites. J. Proteome Res. 9(8), 3766-3780 (2010).