A natural antibiotic and anti-inflammatory alcohol
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Patchouli Alcohol

Item No. 18450

Technical Information
Formal Name
(1R,4S,4aS,6R,8aS)-octahydro-4,8a,9,9-tetramethyl-1,6-methanonaphthalen-1(2H)-ol
CAS Number
5986-55-0
Synonyms
  • (-)-Patchouli Alcohol
  • Patchoulol
Molecular Formula
C15H26O
Formula Weight
Purity
≥95%
A crystalline solid
DMF: 25 mg/mlDMSO: 16 mg/mlDMSO:PBS(pH 7.2) (1:2): 0.3 mg/mlEthanol: 16 mg/ml
SMILES
[H][C@]1(C2)[C@@H](C)CC[C@@]3(O)C(C)(C)[C@]2([H])CC[C@]31C
InChi Code
InChI=1S/C15H26O/c1-10-5-8-15(16)13(2,3)11-6-7-14(15,4)12(10)9-11/h10-12,16H,5-9H2,1-4H3/t10-,11+,12-,14-,15+/m0/s1
InChi Key
GGHMUJBZYLPWFD-CUZKYEQNSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    Product Description

    Patchouli alcohol is a sesquiterpene alcohol found in patchouli oil. It has antibacterial, antifungal, and antiviral actions.1,2,3 Patchouli alcohol also suppresses inflammation induced by lipopolysaccharide in vivo.4 Topical application of patchouli alcohol accelerates recovery from ultraviolet irradiation-induced skin damage through antioxidant and anti-inflammatory effects.5

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Zhang, R., Yan, P., Li, Y., et alA pharmacokinetic study of patchouli alcohol after a single oral administration of patchouli alcohol or patchouli oil in rats. Eur. J. Drug Metab. Pharmacokinet. 41(4), 441-448 (2015).

    2. Wu, H., Li, B., Wang, X., et alInhibitory effect and possible mechanism of action of patchouli alcohol against influenza A (H2N2) virus. Molecules 16(8), 6489-6501 (2011).

    3. Yu, X.D., Xie, J.H., Wang, Y.H., et alSelective antibacterial activity of patchouli alcohol against Helicobacter pylori based on inhibition of urease. Phytother. Res. 29(1), 67-72 (2015).

    4. Yu, J.L., Zhang, X.S., Xue, X., et alPatchouli alcohol protects against lipopolysaccharide-induced acute lung injury in mice. J. Surg. Res. 194(2), 537-543 (2015).

    5. Feng, X.X., Yu, X.T., Li, W.J., et alEffects of topical application of patchouli alcohol on the UV-induced skin photoaging in mice. Eur. J. Pharm. Sci. 63, 113-123 (2014).