A natural flavonoid and antioxidant
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Quercetin 3-D-galactoside

Item No. 18648

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
2-(3,4-dihydroxyphenyl)-3-(β-D-galactopyranosyloxy)-5,7-dihydroxy-4H-1-benzopyran-4-one
CAS Number
482-36-0
Synonyms
  • Hyperoside
  • NSC 407304
  • Quercetin-3-O-galactoside
Molecular Formula
C21H20O12
Formula Weight
464.4
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
DMF: 10 mg/mlDMSO: 10 mg/mlPBS (pH 7.2): 0.3 mg/ml
λmax
256, 359 nm
SMILES
OC1=CC(O)=C(C(C(O[C@@H]2O[C@H](CO)[C@H](O)[C@H](O)[C@H]2O)=C(C3=CC=C(O)C(O)=C3)O4)=O)C4=C1
InChi Code
InChI=1S/C21H20O12/c22-6-13-15(27)17(29)18(30)21(32-13)33-20-16(28)14-11(26)4-8(23)5-12(14)31-19(20)7-1-2-9(24)10(25)3-7/h1-5,13,15,17-18,21-27,29-30H,6H2/t13-,15+,17+,18-,21+/m1/s1
InChi Key
OVSQVDMCBVZWGM-DTGCRPNFSA-N
Origin
Plant/Abelmoschus manihot (L.) Medic.
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    1 mg

    $36

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    5 mg

    $153

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    10 mg

    $268

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    25 mg

    $462

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    Product Description

    Quercetin (Item No. 10005169) is an antioxidant flavonoid compound found in many plants and fruits.1 Quercetin 3-D-galactoside, commonly known as hyperoside, is a 3-O-galactoside of quercetin that can be found in a wide range of plants.2,3 It has powerful antioxidant action through its ability to scavenge free radicals (IC50s = 3.54 and 5.44 µg/ml in ABTS and DPPH assays, respectively).2,4,5 Quercetin 3-D-galactoside downregulates the advanced glycation end-product (AGE) receptor in AGE-stimulated ECV304 cells and stimulates osteogenic differentiation of human osteosarcoma cells.6,7

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Gschwendt, M., Horn, F., Kittstein, W., et al. Inhibition of the calcium- and phospholipid-dependent protein kinase activity from mouse brain cytosol by quercetin. Biochem. Biophys. Res. Commun. 117(2), 444-447 (1983).

    2. Bernatoniene, J., Masteikova, R., Majine, D., et al. Free radical-scavenging activities of Crataegus monogyna extracts. Medicina (Kaunas) 44(9), 706-712 (2008).

    3. Jurikova, T., Sochor, J., Rop, O., et al. Polyphenolic profile and biological activity of Chinese hawthorn (Crataegus pinnatifida BUNGE) fruits. Molecules 17(12), 14490-14509 (2012).

    4. Zhang, Z., Sethiel, M.S., Shen, W., et al. Hyperoside downregulates the receptor for advanced glycation end products (RAGE) and promotes proliferation in ECV304 cells via the c-Jun N-terminal kinases (JNK) pathway following stimulation by advanced glycation end-products in vitro. Int. J. Mol. Sci. 14(11), 22697-22707 (2013).

    5. Zhang, N., Ying, M.D., Wu, Y.P., et al. Hyperoside, a flavonoid compound, inhibits proliferation and stimulates osteogenic differentiation of human osteosarcoma cells. PLoS One 9(7), (2014).