A biosynthetic intermediate
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4-Aminobenzoic Acid (sodium salt)

Item No. 18659

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
4-amino-benzoic acid, monosodium salt
CAS Number
555-06-6
Synonyms
  • PABA
  • p-Aminobenzoic Acid
Molecular Formula
C7H6NO2 • Na
Formula Weight
159.1
Purity
≥98%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 10 mg/ml
λmax
284 nm
SMILES
[O-]C(C1=CC=C(N)C=C1)=O.[Na+]
InChi Code
InChI=1S/C7H7NO2.Na/c8-6-3-1-5(2-4-6)7(9)10;/h1-4H,8H2,(H,9,10);/q;+1/p-1
InChi Key
XETSAYZRDCRPJY-UHFFFAOYSA-M
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

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    25 g

    $41

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    50 g

    $72

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    100 g

    $119

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    250 g

    $235

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    Product Description

    4-Aminobenzoic acid, commonly known as PABA, is an intermediate in the synthesis of tetrahydrofolic acid in many non-mammalian organisms, including bacteria and fungi. 1 Folates, like tetrahydrofolic acid, have critical roles in the metabolism of nucleic acid precursors and several amino acids, as well as in methylation reactions.2 In mammals, PABA is metabolized by a variety of enzymes, including N-acetyltransferases.3 It may also be utilized by bacteria or fungi that are living in mammalian organisms, including those resident in the gut.4

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Wegkamp, A., van Oorschot, W., de Vos, W.M., et al. Characterization of the role of para-aminobenzoic acid biosynthesis in folate production by Lactococcus lactis. Appl. Environ. Microbiol. 73(8), 2673-2681 (2007).

    2. Ragsdale, S.W. Catalysis of methyl group transfers involving tetrahydrofolate and B12. Vitam. Horm. 79, 293-324 (2008).

    3. Föllmann, W., Blaszkewicz, M., Behm, C., et al. N-Acetylation of p-aminobenzoic acid and p-phenylenediamine in primary porcine urinary bladder epithelial cells and in the human urothelial cell line 5637. J. Toxicol. Environ. Health A 75(19-20), 1206-1215 (2012).

    4. Rossi, M., Amaretti, A., and Raimondi, S. Folate production by probiotic bacteria. Nutrients 3(1), 118-134 (2011).