An aryl hydrocarbon receptor agonist
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Small Molecule Modulators
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5-methyl Chrysene

Item No. 18677

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5-methyl-chrysene
CAS Number
3697-24-3
Synonyms
  • NSC 407620
Molecular Formula
C19H14
Formula Weight
242.3
Purity
≥98%
Formulation
A crystalline solid
Solubility(Learn about Variance in Solubility)
Chloroform: SolubleMethanol: Soluble
λmax
218, 269, 300, 312, 326 nm
SMILES
CC1=CC2=CC=CC=C2C3=C1C(C=CC=C4)=C4C=C3
InChi Code
InChI=1S/C19H14/c1-13-12-15-7-3-4-8-16(15)18-11-10-14-6-2-5-9-17(14)19(13)18/h2-12H,1H3
InChi Key
GOHBXWHNJHENRX-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Room temperature in continental US; may vary elsewhere
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    5 mg

    $169

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    10 mg

    $268

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    25 mg

    $629

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    Product Description

    5-methyl Chrysene is a carcinogenic polycyclic aromatic hydrocarbon consisting of four fused rings and acts as an aryl hydrocarbon receptor agonist.1 It is produced by the incomplete combustion of organic matter and found primarily in gasoline exhaust and tobacco smoke.1 5-methyl Chrysene can be activated to mutagenic metabolites by cytochrome P450 1A1 and 1B1.1

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Ahmad, S., Kabler, S.l., Rudd, L., et al. Cytotoxicity and mutagenicity of 5-methylchrysene and its 1,2-dihydrodiol in V79MZ cells modified to express human CYP1A1 or CYP1B1, in the presence or absence of human GSTP1 coexpression. Toxicol. Lett. 183(1-3), 99-104 (2008).