An NBD-hexanoic acid fluorophore
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C-6 NBD

Item No. 18871

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
6-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-hexanoic acid
CAS Number
88235-25-0
Synonyms
  • C6-NBD
  • NBD Hexanoic Acid
  • NBD-X
  • ​6-(7-Nitrobenzofurazan-4-ylamino)hexanoic Acid
Molecular Formula
C12H14N4O5
Formula Weight
294.3
Purity
≥96%
Emission
535 nm
Formulation (Request formulation change)
A solid
Solubility(Learn about Variance in Solubility)
DMSO: Soluble
SMILES
OC(CCCCCNC1=CC=C([N+]([O-])=O)C2=NON=C21)=O
InChi Code
InChI=1S/C12H14N4O5/c17-10(18)4-2-1-3-7-13-8-5-6-9(16(19)20)12-11(8)14-21-15-12/h5-6,13H,1-4,7H2,(H,17,18)
InChi Key
DJFNQJJTTPMBIL-UHFFFAOYSA-N
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
Certificates of Analysis & Batch Specific Data

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    200 mg

    $208

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    1 g

    $676

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    Product Description

    C-6 NBD is a derivative of the environmentally sensitive fluorophore nitrobenzoxadiazole (NBD; absorbance 465 nm, emission 535 nm). It is modified with a hexanoic acid tail, which provides a reactive carboxylic acid site. C-6 NBD has been used to synthesize a variety of fluorescently tagged compounds for research purposes.1,2,3,4,5

    WARNING This product is not for human or veterinary use.

    References & Product Citations
    Product Description References

    1. Lipsky, N.G., and Pagano, R.E. A vital stain for the golgi apparatus. Science 228, 745-757 (1985).

    2. Paul, P., Kamisaka, Y., Marks, D.L., et al. Purification and characterization of UDP-glucose: Ceramide glucosyltransferase from rat liver Golgi membranes. The Journal of Biological Chemisty 271(4), 2287-2293 (1996).

    3. Zurzolo, C., van't Hof, W., van Meer, G., et al. VIP21/caveolin, glycosphingolipid clusters and the sorting of glycosylphosphatidylinositol-anchored proteins in epithelial cells. EMBO J. 13, 42-53 (1994).

    4. Engfeldt, T., Renberg, B., Brumer, J., et al. Chemical synthesis of triple-labelled three-helix bundle binding proteins for specific fluorescent detection of unlabelled protein. Chembiochem 6(6), 1043-1050 (2005).

    5. Escoffre, J.M., Bellard, E., Faurie, C., et al. Membrane disorder and phospholipid scrambling in electropermeabilized and viable cells. Biochim. Biophys. Acta 1838(7), 1701-1709 (2014).