An intermediate in several biochemical pathways
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5-Phospho-D-ribose 1-diphosphate (sodium salt hydrate)

Item No. 18897

Product Insert (PDF)Safety Data Sheet (SDS) (PDF)
Technical Information
Formal Name
5-(dihydrogen phosphate) 1-(trihydrogen diphosphate) α-D-ribofuranose, pentasodium salt hydrate
Synonyms
  • Phosphoribosyl Pyrophosphate
  • P-rib-PP
  • PRPP
Molecular Formula
C5H8O14P3 • 5Na [XH2O]
Formula Weight
385.0
Purity
≥75%
Formulation (Request formulation change)
A crystalline solid
Solubility(Learn about Variance in Solubility)
PBS (pH 7.2): 10 mg/ml
SMILES
O[C@H]1[C@@H](OP(OP([O-])([O-])=O)([O-])=O)O[C@H](COP([O-])([O-])=O)[C@H]1O.[Na+].[Na+].[Na+].[Na+].[Na+]
InChi Code
InChI=1S/C5H13O14P3.5Na/c6-3-2(1-16-20(8,9)10)17-5(4(3)7)18-22(14,15)19-21(11,12)13;;;;;/h2-7H,1H2,(H,14,15)(H2,8,9,10)(H2,11,12,13);;;;;/q;5*+1/p-5/t2-,3-,4-,5-;;;;;/m1...../s1
InChi Key
UJNGSXHPBPBVKF-LVGJVSMDSA-I
Shipping & Storage Information
Storage
-20°C
Shipping
Wet ice in continental US; may vary elsewhere
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    5 mg

    $61

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    10 mg

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    25 mg

    $152

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    100 mg

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    Product Description

    5-Phospho-D-ribose 1-diphosphate (PRPP) is a natural intermediate involved in the pentose phosphate pathway leading to purine, pyrimidine, and histidine metabolism. It is also an intermediate in the synthesis of plant hormones, alkaloids, and other secondary metabolites from glucose. Several phosphoribosyltransferases (PRTases) use PRPP as a substrate to add a 5-phosphoribosyl group to another substrate, as in the production of adenosine monophosphate from adenine and PRPP by adenine PRTase.

    WARNING This product is not for human or veterinary use.